Evaluation of Glucose Metabolism in Acute Myocardial Infarction by Glycated Albumin and Glycated Haemoglobin

Objectives To detect whether persisting or transient glucose metabolism disorder is responsible for admission hyperglycemia in patients with acute myocardic infarction(AMI).Methods Two groups of patients were enrolled:AMI group and control group.Fasting plasma glucose,2 hours plasma glucose,glycated albumin(GA) and glycated haemoglobin (HbA1c) were measured at baseline in both groups and 30 days after AMI attack in AMI group.Results(1) There were no significant differences in baseline characteristics between both groups;(2) Compared with the control group,the levels of GA and HbAlc in AMI group at baseline were significantly higher.(3) At 30 day follow-up in AMI group,both FBG and 2hPG decreased to normal values,HbAl c did not change,but only GA kept on increasing. Conclusions Hyperglycemia on admission in patients with AMI resulted from both preexisting metabolic disorder and stress reaction as well.GA is the only indicator that could recall the exaggeration of glucose metabolic disorder during AMI attack at 30 day follow-up.