Human umbilical cord mesenchymal stem cells and the treatment of spinal cord injury

被引：0
|
作者：
CAO Fujiang and FENG Shiqing Department of OrthopaedicsGeneral Hospital of Tianjin Medical UniversityTianjin China [300052 ]
机构：
来源：
中华医学杂志(英文版) | 2009年 / 02期
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中图分类号：
R686 [筋腱、韧带、滑囊疾病及损伤];
学科分类号：
1002 ; 100210 ;
摘要：
Objective To review the recent studies about human umbilical cord mesenchymal stem cells (hUCMSCs) andadvances in the treatment of spinal cord injury.Data sources Published articles (1983-2007) about hUCMSCs and spinal cord injury were selected using Medline.Study selection Articles selected were relevant to development of mesenchymal stem cells (MSCs) for transplantation inspinal cord injury therapy.Of 258 originally identified articles 51 were selected that specifically addressed the stated purpose.Results Recent work has revealed that hUCMSCs share most of the characteristics with MSCs derived from bonemarrow and are more appropriate to transplantation for cell based therapies.Conclusions Human umbilical cord could be regarded as a source of MSCs for experimental and clinical needs.Iraddition,as a peculiar source of stem cells,hUCMSCs may play an important role in the treatment of spinal cord injury.
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页码：225 / 231
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