A small-molecule approach towards the Fountain of Youth: chemically induced pluripotent stem cells

被引：0
|
作者：
Tuoping Luo [1 ]
机构：
[1] the College of Chemistry and Molecular Engineering, Peking University
来源：
National Science Review | 2022年 / 9卷 / 11期
关键词：
D O I：
暂无
中图分类号：
Q254 [细胞分化];
学科分类号：
摘要：
Generation and regeneration as an answer to disease treatment has been around for some time. Yet never have we come so close to reaching such ’life-altering’ capabilities. Today, the field of regenerative medicine research focuses on replacing non-functional or dead cells with healthy ones, in order to repair or regenerate tissues and organs to restore normal functions.
引用
收藏
页码：58 / 62
页数：5
相关论文
共 50 条
  • [21] Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors
    Chambers, Stuart M.
    Qi, Yuchen
    Mica, Yvonne
    Lee, Gabsang
    Zhang, Xin-Jun
    Niu, Lei
    Bilsland, James
    Cao, Lishuang
    Stevens, Edward
    Whiting, Paul
    Shi, Song-Hai
    Studer, Lorenz
    NATURE BIOTECHNOLOGY, 2012, 30 (07) : 715 - +
  • [22] Combined small-molecule inhibition accelerates developmental timing and converts human pluripotent stem cells into nociceptors
    Stuart M Chambers
    Yuchen Qi
    Yvonne Mica
    Gabsang Lee
    Xin-Jun Zhang
    Lei Niu
    James Bilsland
    Lishuang Cao
    Edward Stevens
    Paul Whiting
    Song-Hai Shi
    Lorenz Studer
    Nature Biotechnology, 2012, 30 : 715 - 720
  • [23] Simple and Robust Differentiation of Human Pluripotent Stem Cells toward Chondrocytes by Two Small-Molecule Compounds
    Kawata, Manabu
    Mori, Daisuke
    Kanke, Kosuke
    Hojo, Hironori
    Ohba, Shinsuke
    Chung, Ung-il
    Yano, Fumiko
    Masaki, Hideki
    Otsu, Makoto
    Nakauchi, Hiromitsu
    Tanaka, Sakae
    Saito, Taku
    STEM CELL REPORTS, 2019, 13 (03): : 530 - 544
  • [24] Small Molecule Mesengenic Induction of Human Induced Pluripotent Stem Cells to Generate Mesenchymal Stem/Stromal Cells
    Chen, Yen Shun
    Pelekanos, Rebecca A.
    Ellis, Rebecca L.
    Horne, Rachel
    Wolvetang, Ernst J.
    Fisk, Nicholas M.
    STEM CELLS TRANSLATIONAL MEDICINE, 2012, 1 (02) : 83 - 95
  • [25] Small Molecule-Based Retinal Differentiation of Human Embryonic Stem Cells and Induced Pluripotent Stem Cells
    Zhu, Jie
    Lamba, Deepak A.
    BIO-PROTOCOL, 2018, 8 (12):
  • [26] Stem Cells, Aging, and the Fountain of Youth
    Peters, Ted
    THEOLOGY AND SCIENCE, 2012, 10 (03) : 221 - 223
  • [27] Of Cytometry, Stem Cells and Fountain of Youth
    Dariusz Galkowski
    Mariusz Z. Ratajczak
    Janusz Kocki
    Zbigniew Darzynkiewicz
    Stem Cell Reviews and Reports, 2017, 13 : 465 - 481
  • [28] Stem cells - The chameleon fountain of youth
    Kereiakes, DJ
    CIRCULATION, 2003, 107 (07) : 939 - 940
  • [29] Of Cytometry, Stem Cells and Fountain of Youth
    Galkowski, Dariusz
    Ratajczak, Mariusz Z.
    Kocki, Janusz
    Darzynkiewicz, Zbigniew
    STEM CELL REVIEWS AND REPORTS, 2017, 13 (04) : 465 - 481
  • [30] Highly efficient and expedited hepatic differentiation from human pluripotent stem cells by pure small-molecule cocktails
    Du, Cong
    Feng, Yuan
    Qiu, Dongbo
    Xu, Yan
    Pang, Mao
    Cai, Nan
    Xiang, Andy Peng
    Zhang, Qi
    STEM CELL RESEARCH & THERAPY, 2018, 9
12345