Design,synthesis and antimicrobial activities of 1,2,3-triazole derivatives

被引：1
|
作者：
Xu Zhao a
机构：
来源：
Chinese Chemical Letters | 2012年 / 23卷 / 08期
基金：
中国国家自然科学基金;
关键词：
1-(4-Substituted phenyl)-4-(4-bromophenyl)-5-(halo-o-hydroxyphenyl)imino-1,2,3-triazoles; 1-(4-Substituted phenyl)-4-(4-bromophenyl)-5-amino-1,2,3-triazoles; Synthesis; Antimicrobial activity;
D O I：
暂无
中图分类号：
O626 [杂环化合物];
学科分类号：
070303 ; 081704 ;
摘要：
Fifteen 1-(4-substituted phenyl)-4-(4-bromophenyl)-5-(halo-o-hydroxyphenyl)imino-1,2,3-triazoles were designed and synthesized based on rational combination of 1,2,3-triazoles and(halo)o-hydroxyphenyl group according to the superposition principle of reinforcement of biological activities.All the compounds were tested to an in vitro antimicrobial screening against M.a.and E.c..Compounds IIe-IIo exhibited more potent antimicrobial activities against M.a.and E.c.than triclosan and fluconazole,which provided valuable information to further study of novel antimicrobial research.
引用
收藏
页码：933 / 935
页数：3
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