One-pot Synthesis of Isoxazolines Using Soluble Polymer-supported Acrylates

被引：0
|
作者：
Lan TAO
机构：
来源：
Chinese Chemical Letters | 2005年 / 04期
关键词：
Isoxazolines; 1; 3-dipolar cycloaddition; soluble polymer; liquid-phase synthesis; polythylene glycol;
D O I：
暂无
中图分类号：
O631.3 [高聚物的化学性质];
学科分类号：
070305 ; 080501 ; 081704 ;
摘要：
An efficient and rapid parallel liquid-phase synthesis of isoxazolines has been reported. The one-pot three-component reaction of polyethylene glycol-supported acrylates, aldehydes and hydroxylamine hydrochloride in the presence of chloramine-T in methanol gave the corresponding PEG-supported isoxazolines, which can be cleaved from the support under mild condition to afford isoxazolines in good yields (>80%) and high purities (>86%).
引用
收藏
页码：440 / 442
页数：3
相关论文
共 50 条
  • [31] Soluble polymer-supported organocatalysts
    Yang, Yun-Chin
    Bergbreiter, David E.
    [J]. PURE AND APPLIED CHEMISTRY, 2013, 85 (03) : 493 - 509
  • [32] One-Pot Synthesis of Furans from Isoxazolines with Iron as Reducing Agent
    Jiang, Dahong
    Chen, Yuanwei
    [J]. LETTERS IN ORGANIC CHEMISTRY, 2010, 7 (08) : 661 - 665
  • [33] Green Organocatalytic Synthesis of Isoxazolines via a One-Pot Oxidation of Allyloximes
    Triandafillidi, Ierasia
    Kokotos, Christoforos G.
    [J]. ORGANIC LETTERS, 2017, 19 (01) : 106 - 109
  • [34] A facile one-pot solid-phase synthesis of oxazolidin-2-ones using polymer-supported 2-hydroxyalkyl selenide reagent
    Hu, Qiao-Sheng
    Sheng, Shou-Ri
    Lin, Shu-Ying
    Wei, Mei-Hong
    Xin, Qin
    Liu, Xiao-Ling
    [J]. JOURNAL OF CHEMICAL RESEARCH, 2007, (02) : 74 - 75
  • [35] POLYMER-SUPPORTED BASES .3. SYNTHESIS OF PHOSPHATIDYLCHOLINES USING POLYMER-SUPPORTED AMINOPYRIDINES
    TOMOI, M
    GOTO, M
    KAKIUCHI, H
    NOGUCHI, Y
    [J]. MAKROMOLEKULARE CHEMIE-RAPID COMMUNICATIONS, 1985, 6 (06): : 397 - 401
  • [36] A one-pot rapid synthesis of dithiocarbamates from alcohols using a polymer supported diethyl dithiocarbamate anion
    Bandgar, BP
    Sadavarte, VS
    Uppalla, LS
    [J]. JOURNAL OF CHEMICAL RESEARCH-S, 2000, (09): : 450 - 451
  • [37] One-pot synthesis of N-allylthioureas using supported reagents
    Aoyama, T
    Murata, S
    Nagata, Y
    Takido, T
    Kodomari, M
    [J]. TETRAHEDRON LETTERS, 2005, 46 (29) : 4875 - 4878
  • [38] One-pot synthesis of 2-aminothiazoles using supported reagents
    Kodomari, M
    Aoyama, T
    Suzuki, Y
    [J]. TETRAHEDRON LETTERS, 2002, 43 (09) : 1717 - 1720
  • [39] Phthalocyanines as an alternative to soluble polymer-supported platforms in organic synthesis
    Clifford C. Leznoff
    Sandra V. Agostino
    [J]. Molecular Diversity, 2005, 9 : 63 - 66
  • [40] Phthalocyanines as an alternative to soluble polymer-supported platforms in organic synthesis
    Leznoff, Clifford C.
    Agostino, Sandra V.
    [J]. MOLECULAR DIVERSITY, 2005, 9 (1-3) : 63 - 66
12345