Analysis on the risk factors of intracranial infection secondary to traumatic brain injury

<italic>Objective:</italic> To discuss the characteristics and risk factors for intracranial infection post traumatic brain injury to prevent and better the clinical care. <italic>Methods:</italic> Retrospective study of 520 patients with traumatic brain injury were included, 308 male and 212 female. The risky factors of intracranial infection were identified. <italic>Results:</italic> Thirty two cases (6.54%, 32/520) of intracranial infection were diagnosed. Intracranial infection most likely happened 4-10 days after injury. Cerebrospinal fluid leakage, drainage, multiple craniotomies were significant related to intracranial infection. Logistic regression predicted cerebrospinal fluid leakage and drainage as independent factors. <italic>Conclusion:</italic> Intracranial infection is a serious complication after traumatic brain injury. Patients with drainage or cerebrospinal fluid leakage are more risky for intracranial infection. Aggressive precaution should be taken to better outcome.