Metabolites of Icariin in Rat Bile Following Oral Administration

被引：0
|
作者：
Feng QIU
Qing Song TAN
Ying Jie CHEN
Yoshihiro KANO
Xin Sheng YAO(Shenyang Pharmaceutical University
机构：
来源：
Chinese Chemical Letters | 1998年 / 06期
关键词：
Icariin; icariside; Ⅱ; icaritin; 3-O-α-L-rhamnopyranosyl-7-O-β-D-glucopyranuronoside; metabolite;
D O I：
暂无
中图分类号：
O629 [天然化合物];
学科分类号：
070303 ; 081704 ;
摘要：
The biliary metabolites of orally administered icedin in rats were investigated. Twometabolites B-1 and B-2 were isolated and idenhfied as icaritin 3 -O-α-L-rhamnopyranosyl-7 -O- β-D-glucopyranuronoside and icedside Ⅱ, respectively, on the basis of chemical and spectroscopicevidences.
引用
收藏
页码：549 / 552
页数：4
相关论文
共 50 条
  • [21] Pharmacokinetics of sanguinarine, chelerythrine, and their metabolites in broiler chickens following oral and intravenous administration
    Hu, Nan-Xi
    Chen, Mei
    Liu, Yi-Song
    Shi, Qi
    Yang, Bo
    Zhang, Huan-Cheng
    Cheng, Pi
    Tang, Qi
    Liu, Zhao-Ying
    Zeng, Jian-Guo
    JOURNAL OF VETERINARY PHARMACOLOGY AND THERAPEUTICS, 2019, 42 (02) : 197 - 206
  • [22] BEHAVIORAL THERMOREGULATION IN THE RAT FOLLOWING THE ORAL-ADMINISTRATION OF ETHANOL
    GORDON, CJ
    FOGELSON, L
    MOHLER, F
    STEAD, AG
    REZVANI, AH
    ALCOHOL AND ALCOHOLISM, 1988, 23 (05): : 383 - 390
  • [23] ALLOXAN RESPONSE FOLLOWING PROLONGED ORAL ADMINISTRATION OF THIOUREAIN THE RAT
    MANN, DE
    HIESTAND, WA
    ANATOMICAL RECORD, 1951, 111 (03): : 578 - 578
  • [24] RETENTION OF CADMIUM IN THE DUODENUM OF THE RAT FOLLOWING ORAL-ADMINISTRATION
    PHILLPOTTS, CJ
    TOXICOLOGY, 1979, 14 (03) : 245 - 253
  • [25] PARTIAL STERILITY FOLLOWING ORAL ADMINISTRATION OF SULFAGUANIDINE IN THE MALE RAT
    ROGERS, PV
    ANATOMICAL RECORD, 1955, 121 (02): : 357 - 357
  • [26] DISTRIBUTION OF VANADATE IN THE RAT FOLLOWING SUBCUTANEOUS AND ORAL ROUTES OF ADMINISTRATION
    ALBAYATI, MA
    RAABE, OG
    GIRI, SN
    KNAAK, JB
    JOURNAL OF THE AMERICAN COLLEGE OF TOXICOLOGY, 1991, 10 (02): : 233 - 241
  • [27] CHARACTERIZATION OF METABOLITES OF ELLIPTICINE IN RAT BILE
    BRANFMAN, AR
    BRUNI, RJ
    REINHOLD, VN
    SILVEIRA, DM
    CHADWICK, M
    YESAIR, DW
    DRUG METABOLISM AND DISPOSITION, 1978, 6 (05) : 542 - 548
  • [28] CONJUGATED METABOLITES OF ESTRIOL IN RAT BILE
    NAMBARA, T
    KAWARADA, Y
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1975, 23 (03) : 698 - 700
  • [29] PHENOLIC METABOLITES OF MIDAZOLAM IN RAT BILE
    KOLIS, SJ
    WOO, GK
    WILLIAMS, TH
    SASSO, GJ
    SCHWARTZ, MA
    FEDERATION PROCEEDINGS, 1981, 40 (03) : 733 - 733
  • [30] STUDIES ON METABOLITES IN URINE AND FECES OF RAT AFTER ORAL ADMINISTRATION OF RADIOACTIVE PANTETHINE
    NAKAMURA, H
    TAMURA, Z
    CHEMICAL & PHARMACEUTICAL BULLETIN, 1972, 20 (09) : 2008 - +
12345