Repeated-Batch and Continuous Production of L-Lactic Acid by Rhizopus oryzae Immobilized in Calcium Alginat Beads:ReactorPerformance and Kinetic Model

被引:1
|
作者
李学梅
林建平
刘茉娥
岑沛霖
机构
基金
中国国家自然科学基金;
关键词
L-lactic acid; immobilized fermentation; bioreactor; kinetic model; R.oryzae;
D O I
暂无
中图分类号
TQ018 [数学模型及放大];
学科分类号
0703 ;
摘要
Repeated-batch and continuous production of L-lactic acid by immobilized Rhizopusoryzae with calcium alginate entrapment method in a three-phase fluidized-bed bioreactor was stud-ied.The operation conditions were optimized.The productivity based on total reactor volume wasabout 3 times higher than that with free cells in a traditional stirred tank bioreactor.A mathemat-ical model was proposed and the model predictions were in good agreement with the experimentaldat.
引用
收藏
页码:52 / 61
页数:10
相关论文
共 50 条
  • [21] PRODUCTION OF L(+)-LACTIC ACID USING IMMOBILIZED RHIZOPUS-ORYZAE - REACTOR PERFORMANCE-BASED ON KINETIC-MODEL AND SIMULATION
    HAMAMCI, H
    RYU, DDY
    APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY, 1994, 44 (02) : 125 - 133
  • [22] Extractive fermentation of L-lactic acid with immobilized Rhizopus oryzae in a three-phase fluidized bed
    Lin, Jianping
    Zhou, Maohong
    Zhao, Xiaowei
    Luo, Shiyi
    Lu, Yinghua
    CHEMICAL ENGINEERING AND PROCESSING-PROCESS INTENSIFICATION, 2007, 46 (05) : 369 - 374
  • [23] Production of L-lactic acid from Corn Starch Hydrolysate by Immobilized Rhizopus Oryzae on a New Asterisk-shaped Matrix
    Chen, Xin
    Zhang, Bingbing
    Wang, Yuanliang
    Luo, Yanfeng
    Wang, Runguang
    Ren, Huiqing
    Xu, Hongji
    RENEWABLE AND SUSTAINABLE ENERGY, PTS 1-7, 2012, 347-353 : 1193 - 1197
  • [24] A new method studying the kinetics of l-lactic acid production by pellets Rhizopus oryzae in semi-continuous fermentation
    Xuefeng Wu
    Shaotong Jiang
    Min Zhang
    Shuizhong Luo
    Xingjiang Li
    Lijun Pan
    Zhi Zheng
    Mo Liu
    Annals of Microbiology, 2015, 65 : 1473 - 1480
  • [25] A new method studying the kinetics of L-lactic acid production by pellets Rhizopus oryzae in semi-continuous fermentation
    Wu, Xuefeng
    Jiang, Shaotong
    Zhang, Min
    Luo, Shuizhong
    Li, Xingjiang
    Pan, Lijun
    Zheng, Zhi
    Liu, Mo
    ANNALS OF MICROBIOLOGY, 2015, 65 (03) : 1473 - 1480
  • [26] Enhanced effectiveness of Rhizopus oryzae by immobilization in a static bed fermentor for L-lactic acid production
    Pimtong, Varunee
    Ounaeb, Siriporn
    Thitiprasert, Sitanan
    Tolieng, Vasana
    Sooksai, Sarintip
    Boonsombat, Ruethairat
    Tanasupawat, Somboon
    Assabumrungrat, Suttichai
    Thongchul, Nuttha
    PROCESS BIOCHEMISTRY, 2017, 52 : 44 - 52
  • [27] L-lactic acid production by Aspergillus brasiliensis overexpressing the heterologous ldha gene from Rhizopus oryzae
    Liaud, Nadege
    Rosso, Marie-Noelle
    Fabre, Nicolas
    Crapart, Sylvaine
    Herpoel-Gimbert, Isabelle
    Sigoillot, Jean-Claude
    Raouche, Sana
    Levasseur, Anthony
    MICROBIAL CELL FACTORIES, 2015, 14
  • [28] L-lactic acid production by Aspergillus brasiliensis overexpressing the heterologous ldha gene from Rhizopus oryzae
    Nadège Liaud
    Marie-Noëlle Rosso
    Nicolas Fabre
    Sylvaine Crapart
    Isabelle Herpoël-Gimbert
    Jean-Claude Sigoillot
    Sana Raouche
    Anthony Levasseur
    Microbial Cell Factories, 14
  • [29] L-lactic acid production using immobilized Rhizopus oryzae in a three-phase fluidized-bed with simultaneous product separation by electrodialysis
    Xuemei, L
    Jianping, L
    Mo'e, L
    Peilin, C
    BIOPROCESS ENGINEERING, 1999, 20 (03): : 231 - 237
  • [30] L-lactic acid production using immobilized Rhizopus oryzae in a three-phase fluidized-bed with simultaneous product separation by electrodialysis
    L. Xuemei
    L. Jianping
    L. Mo'e
    C. Peilin
    Bioprocess Engineering, 1999, 20 (3) : 231 - 237