Schwannomas provide insight into the role of p75NTR and merlin in Schwann cells following nerve injury and during regeneration

被引：0

作者：

Elise Cheng ^{[1
]}

Marlan R.Hansen ^{[1
,2
]}

机构：

[1] Department of Otolaryngology – Head and Neck Surgery, University of Iowa Hospitals and Clinics

[2] Department of Neurosurgery, University of Iowa Hospitals and Clinics

来源：

Neural Regeneration Research | 2016年 / 11卷 / 01期

关键词：

cell; NTR; Schwannomas provide insight into the role of p75; JNK;

D O I：

暂无

中图分类号：

R745 [周围神经及神经节疾病];

学科分类号：

1002 ;

摘要：

Peripheral nerve injury leads to Wallerian degeneration of severed axons,leaving the Schwann cell(SC)sheath behind.Denervated SCs may then either survive and remyelinate a regenerating axon,or they may undergo cell death.Because SCs provide trophic support and guidance cues to regenerating nerve fibers,SC loss severely hampers nerve regeneration(Hall,1986).Thus,significant work has sought to characterize the molecular

引用

页码：73 / 74

页数：2

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