Mechanical ventilation(MV)may aggravate lunginjury induced by a variety of injuries,includingintratracheal hydrochloric acid instillation,intratracheallipopolysaccharide(LPS)instillation with or withoutconcurrent saline lavage,intravenous LPS,orintravenous oleic acid.However,the mechanism for thisdetrimental effect of MV is unclear.The purpose of thepresent study was to determine the effect of MV on lunginjury induced by minimal LPS-instillation and on theLPS receptor CDin the lung.
机构:
Univ Fed Rio de Janeiro, Lab Pulm Invest, Carlos Chagas Filho Biophys Inst, Rio De Janeiro, BrazilMahidol Univ, Ramathibodi Hosp, Bangkok, Thailand
Soluri-Martins, Andre
Silva, Pedro L.
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Univ Fed Rio de Janeiro, Lab Pulm Invest, Carlos Chagas Filho Biophys Inst, Rio De Janeiro, BrazilMahidol Univ, Ramathibodi Hosp, Bangkok, Thailand
机构:
Univ Fed Rio de Janeiro, Lab Pulm Invest, Carlos Chagas Filho Biophys Inst, Rio De Janeiro, BrazilMahidol Univ, Ramathibodi Hosp, Bangkok, Thailand
机构:
Univ Toronto, Toronto, ON, Canada
St Michaels Hosp, Keenan Res Ctr, Li Ka Shing Knowledge Inst, Toronto, ON M5B 1W8, CanadaDalhousie Univ, Halifax, NS, Canada
Zhang, H.
Slutsky, A. S.
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机构:
Univ Toronto, Toronto, ON, Canada
St Michaels Hosp, Keenan Res Ctr, Li Ka Shing Knowledge Inst, Toronto, ON M5B 1W8, CanadaDalhousie Univ, Halifax, NS, Canada
机构:
St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, CanadaSt Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, Canada
Parotto, M.
Chan, M. C.
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St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, CanadaSt Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, Canada
Chan, M. C.
Spieth, P. M.
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St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, CanadaSt Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, Canada
Spieth, P. M.
Slutsky, A. S.
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St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, CanadaSt Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, Canada
Slutsky, A. S.
Zhang, H.
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St Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, CanadaSt Michaels Hosp, Li Ka Shing Knowledge Inst, Keenan Res Ctr, Toronto, ON, Canada
机构:
Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, TurkeyIstanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Akinci, OI
Celik, M
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Celik, M
Mutlu, GM
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Mutlu, GM
Martino, JM
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Martino, JM
Tugrul, S
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Tugrul, S
Ozcan, PE
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Ozcan, PE
Yilmazbayhan, D
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Yilmazbayhan, D
Yeldandi, AV
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Yeldandi, AV
Turkoz, KH
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Turkoz, KH
Kiran, B
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Kiran, B
Telci, L
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
Telci, L
Cakar, N
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机构:Istanbul Univ, Istanbul Fac Med, Dept Anesthesiol & Intens Care, TR-34390 Istanbul, Turkey
机构:
Charite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Steiner, E.
Pickerodt, P. A.
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机构:
Charite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Pickerodt, P. A.
Francis, R. C.
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机构:
Charite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Francis, R. C.
Boemke, W.
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机构:
Charite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Boemke, W.
Russ, M.
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机构:
Charite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Russ, M.
Graw, J.
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Charite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Graw, J.
Gonzalez-Lopez, A.
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Charite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Gonzalez-Lopez, A.
Busch, T.
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机构:
Univ Leipzig, Anesthesiol & Operat Intens Care Med, Leipzig, GermanyCharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany
Busch, T.
Swenson, E. R.
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机构:
Seattle VA Med Ctr, Div Pulm Crit Care & Sleep Med, Seattle, WA USACharite Univ Med Berlin, CVK, Anesthesiol & Operat Intens Care Med CCM, Berlin, Germany