Upadacitinib in Patients With Difficult-to-Treat Crohn's Disease

被引：1

作者：

Bezzio, Cristina ^{[1
,2
]}

Franchellucci, Gianluca ^{[1
,2
]}

Savarino, Edoardo, V ^{[3
]}

Mastronardi, Mauro ^{[4
]}

Caprioli, Flavio Andrea ^{[5
,6
]}

Bodini, Giorgia ^{[7
]}

Variola, Angela ^{[8
]}

Scaldaferri, Franco ^{[9
]}

Furfaro, Federica ^{[10
]}

Calabrese, Emma ^{[11
]}

Principi, Maria Beatrice ^{[12
]}

Biscaglia, Giuseppe ^{[13
]}

Marzo, Manuela ^{[14
]}

Michielan, Andrea ^{[15
]}

Cavalli, Carolina ^{[16
]}

Aratari, Annalisa ^{[17
]}

Campigotto, Michele ^{[18
]}

Ceccarelli, Linda ^{[19
]}

Cappello, Maria ^{[20
]}

Saibeni, Simone ^{[21
]}

Balestrieri, Paola ^{[22
]}

Soriano, Alessandra ^{[23
]}

Casini, Valentina ^{[24
]}

Bertani, Lorenzo ^{[25
]}

Barberio, Brigida ^{[3
]}

Conforti, Francesco Simone ^{[5
]}

Danese, Silvio ^{[10
]}

Armuzzi, Alessandro ^{[1
,2
]}

机构：

[1] IRCCS Humanitas Res Hosp, Gastroenterol Dept, IBD Unit, I-20089 Rozzano, Italy

[2] Humanitas Univ, Dept Biomed Sci, Pieve Emanuele, Italy

[3] Univ Padua, Dept Surg Oncol & Gastroenterol, Div Gastroenterol, Padua, Italy

[4] S de Bellis Natl Inst Gastroenterol, Dept Gastroenterol, Castellana Grotte, Italy

[5] Fdn IRCCS CaGranda Osped Maggiore Policlin, Gastroenterol & Endoscopy Unit, Milan, Italy

[6] Univ Milan, Dept Pathophysiol & Transplantat, Milan, Italy

[7] Univ Genoa, Dept Internal Med, IRCCS Policlin San Martino, Genoa, Italy

[8] IRCCS Osped Sacro Cuore Don Calabria, IBD Unit, Negrar Di Valpolicella, Italy

[9] Fdn Policlin Univ A Gemelli IRCCS, Dipartimento Sci Med & Chirurg, Med Interna & Gastroenterol, IBD Unit,CEMAD,Digest Dis Ctr, Rome, Italy

[10] Univ Vita Salute San Raffaele, IRCCS San Raffaele Hosp, Dept Gastroenterol & Endoscopy, Milan, Italy

[11] Univ Roma Tor Vergata, Dept Syst Med, Gastroenterol Unit, Rome, Italy

[12] Univ Bari Aldo Moro, Dept Precis & Regenerat Med & Ionian Area DiMePRe, Gastroenterol Unit, Bari, Italy

[13] Fdn IRCCS Casa Sollievo Sofferenza, Div Gastroenterol, San Giovanni Rotondo, Italy

[14] Veris Delli Ponti Hosp, Div Gastroenterol, Scorrano, Italy

[15] Santa Chiara Hosp, Gastroenterol & Digest Endoscopy Unit, Azienda Prov Serv Sanit APSS, Trento, Italy

[16] Santa Maria Angeli Hosp, Gastroenterol Unit, Pordenone, Italy

[17] S Filippo Neri Hosp, IBD Unit, Rome, Italy

[18] Univ Trieste, Dept Med Surg & Hlth Sci, Trieste, Italy

[19] Univ Pisa, Dept Translat Sci & New Technol Med & Surg, Gastrointestinal Unit, Pisa, Italy

[20] Univ Palermo, ProMISE Dept, Gastroenterol & Hepatol Sect, Palermo, Italy

[21] Rho Hosp, Gastroenterol Unit, ASST Rhodense, Rho, Italy

[22] Campus Biomed Univ, Unit Gastroenterol & Digest Endoscopy, Rome, Italy

[23] IRCCS, Internal Med Dept, Gastroenterol Div, Azienda Unita Sanit Locale, Reggio Emilia, Italy

[24] Bolognini Hosp, Unit Gastroenterol & Digest Endoscopy, ASST Bergamo Est, Seriate, BG, Italy

[25] Tuscany Northwest ASL Pontedera Hosp, Dept Gen Surg & Gastroenterol, Pontedera, Italy

来源：

CROHNS & COLITIS 360 | 2024年 / 6卷 / 04期

关键词：

upadacitinib; Crohn's disease; difficult-to-treat IBD; effectiveness; remission; response;

D O I：

10.1093/crocol/otae060

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Upadacitinib has recently been approved for treating Crohn's disease (CD). Here, we report on the effectiveness and safety of upadacitinib in a cohort of patients with difficult-to-treat CD being cared for at clinical centers across Italy.

引用

页数：5

共 50 条

[21] Treatment of hepatitis C in difficult-to-treat patients
Ferenci, Peter
NATURE REVIEWS GASTROENTEROLOGY & HEPATOLOGY, 2015, 12 (05) : 284 - 292
[22] The management of patients with difficult-to-treat multiple myeloma
Richter, Joshua
Ramasamy, Karthik
Rasche, Leo
Blade, Joan
Zweegman, Sonja
Davies, Faith
Dimopoulos, Meletios
FUTURE ONCOLOGY, 2021, 17 (16) : 2089 - 2105
[23] COPING WITH DIFFICULT-TO-TREAT CANCER-PATIENTS
HYLAND, JM
NOVOTNY, ES
COYNE, L
TRAVIS, JW
PRUYSER, H
BULLETIN OF THE MENNINGER CLINIC, 1984, 48 (04) : 329 - 341
[24] Difficult-to-treat asthma, is it really difficult?
Al-Hajjaj, Mohamed S.
ANNALS OF THORACIC MEDICINE, 2011, 6 (01) : 1 - 2
[25] Treating hepatitis C in "difficult-to-treat" patients
Pawlotsky, JM
NEW ENGLAND JOURNAL OF MEDICINE, 2004, 351 (05): : 422 - 423
[26] Safety and effectiveness of subcutaneous infliximab formulation in difficult-to-treat Crohn's Disease patients with previous exposure to intravenous infliximab: A case-series
Mulinacci, G.
Pirola, L.
Sed, N. Piazza O.
Laffusa, A.
Massironi, M. Fichera S.
Invernizzi, P.
Caprioli, F. A.
Vigano, C.
JOURNAL OF CROHNS & COLITIS, 2024, 18 : I1895 - I1896
[27] The concept of difficult-to-treat disease in rheumatology: where next?
Nagy, Gyorgy
Gunkl-Toth, Lilla
Dorgo, Andras M.
Mcinnes, Iain B.
LANCET RHEUMATOLOGY, 2025, 7 (04): : e274 - e289
[28] Patient and disease characteristics suggest difficult-to-treat PsA
Di Lellis, Maddalena Angela
AKTUELLE RHEUMATOLOGIE, 2025, 50 (02) : 112 - 112
[29] Antihistamine updosing reduces disease activity in patients with difficult-to-treat cholinergic urticaria
Koch, Katja
Weller, Karsten
Werner, Andreas
Maurer, Marcus
Altrichter, Sabine
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY, 2016, 138 (05) : 1483 - +
[30] Quetiapine offers promise for difficult-to-treat psychosis complicating Parkinson's disease
不详
Drugs & Therapy Perspectives, 2001, 17 (18) : 1 - 5

← 1 2 3 4 5 →