Total Synthesis of Dixiamycins A and B via a Late-Stage N-N Bond Formation under Visible Light Photoredox Catalysis

被引：0

作者：

Nandi, Rhituparna ^{[1
]}

Murmu, Ranjit ^{[2
]}

Sadhukhan, Sreyashi ^{[2
]}

Pal, Debopam ^{[2
]}

Biswas, Souvik ^{[2
]}

Das, Bishnu ^{[2
]}

Bisai, Alakesh ^{[1
,2
]}

机构：

[1] Indian Inst Sci Educ & Res Bhopal, Dept Chem, Bhopal 462066, Madhya Pradesh, India

[2] Indian Inst Sci Educ & Res Kolkata, Dept Chem Sci, Mohanpur 741246, W Bengal, India

来源：

ORGANIC LETTERS | 2025年 / 27卷 / 06期

关键词：

DERIVATIVES; ORIDAMYCIN; CARBAZOLE; XIAMYCIN; ACID;

D O I：

10.1021/acs.orglett.5c00083

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Intermolecular oxidative N-N bond formation reactions are quite challenging and are largely uncharted. N-N linked dimeric indolosesquiterpene alkaloids represent an underexplored class of natural products, and strategies for direct dehydrogenative N-N bond formation are limited. Here, we have reported that a late-stage visible-light photoredox catalysis facilitates N-N bond formation, leading to the total syntheses of atropo-diastereomers dixiamycins A (1a) and B (1b).

引用

页码：1531 / 1536

页数：6

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