Reprogramming Adeno-Associated Virus Tropism via Displayed Peptides Tiling Receptor-Ligands in Mice and Non-Human Primates

被引:0
|
作者
Portell, Andrew [1 ]
Ford, Kyle [1 ]
Duy An Le [1 ]
Tarantal, Alice F. [2 ]
Mali, Prashant [1 ]
机构
[1] Univ Calif San Diego, Bioengn, La Jolla, CA USA
[2] Univ Calif Davis, Davis, CA USA
关键词
D O I
暂无
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
313
引用
收藏
页码:167 / 168
页数:2
相关论文
共 39 条
  • [21] Adeno-Associated Viral Vector Delivery of Optimized Human Factor VIII Achieves Therapeutic Factor VIII Levels in Non-Human Primates
    Anguela, Xavier M.
    Elkouby, Liron
    Toso, Raffaella
    DiPietro, Marti
    Davidson, Robert J.
    High, Katherine A.
    Sabatino, Denise E.
    BLOOD, 2015, 126 (23)
  • [22] A Novel Adeno-Associated Viral Variant Shows Superior Retinal Gene Delivery in Non-Human Primates and Human Retinal Cell Models
    Kotterman, Melissa
    Vazin, Tandis V.
    Beliakoff, Ghezal
    Croze, Roxanne
    Byrne, Leah
    Hassanipour, Mohammad
    Schmitt, Christopher
    Wallroth, Marco
    Quezada, Melissa
    Bosch, Aimee
    Fox, Mark
    Khoday, Devi
    Zhu, Lici
    Sullivan, Katie
    Yang, Max
    Steinsapir, Andrew
    Alcamo, Elizabeth
    Holt, Jenny
    Johnson, Leisa
    Davies, Anthony
    Francis, Peter
    Schaffer, David
    Kirn, David
    MOLECULAR THERAPY, 2017, 25 (05) : 49 - 49
  • [23] Whole-Body I-124 PET Imaging of Adeno-Associated Viral Vector Biodistribution in Non-Human Primates
    Ballon, Douglas
    Rosenberg, Jonathan B.
    Kothari, Paresh
    Nikolopoulou, Anastasia
    Fung, Edward
    He, Bin
    De, Bishnu
    Chen, Alvin
    Sondhi, Dolan
    Kaminsky, Stephen M.
    Mozley, P. David
    Babich, John
    Crystal, Ronald G.
    MOLECULAR THERAPY, 2019, 27 (04) : 230 - 230
  • [24] Characterization of the biological effects of adeno-associated virus-mediated gene delivery of neurturin (CERE-120) following injection into the striatum of non-human primates
    Dass, B
    Herzog, CD
    Gasmi, M
    Bakay, RAE
    Chen, E
    Stansell, JE
    Folino, GG
    Anderson, MV
    Bartus, RT
    Kordower, JH
    EXPERIMENTAL NEUROLOGY, 2005, 193 (01) : 243 - 243
  • [25] Specific adeno-associated virus serotypes facilitate efficient gene transfer into human and non-human primate mesenchymal stromal cells
    Chng, Keefe
    Larsen, Stephen R.
    Zhou, Shangzhen
    Wright, J. Fraser
    Martiniello-Wilks, Rosetta
    Rasko, John E. J.
    JOURNAL OF GENE MEDICINE, 2007, 9 (01): : 22 - 32
  • [26] Identification of a cell surface receptor utilized by an engineered BBB-penetrant capsid family with enhanced brain tropism in non-human primates and mice
    Hoffman, B. A.
    Knox, T.
    Moyer, T.
    Shah, I.
    Kaur, R.
    Child, M. A.
    Laks, D. R.
    Nonnenmacher, M.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A32 - A32
  • [27] C3 Complement Inhibitor Limits Transaminitis and Immune Response Following Liver Targeted Adeno-Associated Virus (AAV) Gene Transfer (GT) in Non-Human Primates (NHPs)
    Kropf, Elizabeth
    Smith, Corinne J.
    Kamal, Ali L.
    Markusic, David M.
    Majowicz, Anna
    Kuranda, Klaudia
    MOLECULAR THERAPY, 2024, 32 (04) : 190 - 191
  • [28] Adeno-Associated Virus Type 6 Is Retrogradely Transported in the Non-Human Primate Brain, Implications for Gene Delivery in Huntington's Disease
    San Sebastian, Waldy
    Samaranch, Lluis
    Kells, Adrian P.
    Bringas, John
    Pivirotto, Phillip
    Forsayeth, John
    Bankiewicz, Krystof S.
    MOLECULAR THERAPY, 2013, 21 : S229 - S229
  • [29] Second Generation Adeno-Associated Viral Vector Using a Novel Factor VIII Variant with Improved Secretion Achieves Higher Factor VIII Expression in Non-Human Primates
    Nguyen, Giang N.
    Seleme, Maria C.
    Lindgren, Jonathan R.
    Henriksen, Allysen C.
    Muehlmatt, Amy
    McFadden, Melanie
    Smith, Geary R.
    Sabatino, Denise E.
    BLOOD, 2022, 140 : 1902 - 1903
  • [30] Identification and Characterization of a Highly Conserved Cell Surface Receptor Utilized by Engineered BBB-Penetrant AAV Capsids with Enhanced Brain Tropism in Non-Human Primates and Mice
    Hoffman, Brett
    Knox, Tatiana
    Moyer, Tyler
    Shah, Ishan
    Ren, Xiao-Qin
    Chen, Weitong
    Rouse, Emily
    Maura, Damien
    Nonnenmacher, Mathieu
    MOLECULAR THERAPY, 2024, 32 (04) : 475 - 476