Understanding the Associations between High-Dose Methotrexate Pharmacokinetics and the Risk of Adverse Events in Children and Adolescents with Down Syndrome Associated High-Risk Acute Lymphoblastic Leukemia

被引：0
|
作者：
Westmoreland, Kate D. [1 ,2 ]
Taylor, Zachary L. [3 ,4 ]
Miller, Tamara P. [5 ,6 ]
Chavana, Ashley [7 ]
Rabin, Karen R. [8 ,9 ,10 ]
Brown, Austin L. [11 ]
Bernhardt, Melanie Brooke [12 ]
Schafer, Eric S. [8 ,9 ,10 ]
O'Brien, Maureen M. [13 ,14 ]
Castellino, Sharon M. [5 ,15 ]
Ramsey, Laura B. [3 ,4 ]
机构：
[1] Univ North Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA
[2] Univ N Carolina, Lineberger Comprehens Canc Ctr, Chapel Hill, NC USA
[3] Cincinnati Childrens Hosp, Dept Pediat, Div Pediat Hematol Oncol, Med Ctr, Chapel Hill, NC 27599 USA
[4] Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Div Hematol, Cincinnati, OH USA
[5] Childrens Healthcare Atlanta, Aflac Canc & Blood Disorders Ctr, Cincinnati, OH USA
[6] Emory Univ, Childrens Healthcare Atlanta, Sch Med, Atlanta, GA USA
[7] Baylor Coll Med, Houston, TX USA
[8] Baylor Coll Med, Dept Pediat, Div Hematol Oncol, Houston, TX USA
[9] Texas Childrens Hosp, Canc Ctr, Houston, TX USA
[10] Texas Childrens Hosp, Div Pediat Hematol Oncol, Houston, TX USA
[11] Baylor Coll Med, Dept Pediat, Houston, TX USA
[12] St Jude Childrens Res Hosp, Dept Pharm & Pharmaceut Sci, Memphis, TN USA
[13] Colorado Childrens Hosp, Aurora, CO USA
[14] Univ Colorado, Sch Med, Aurora, CO USA
[15] Emory Univ, Sch Med, Dept Pediat, Div Hematol Oncol & Bone Marrow Transplant, Decatur, GA USA
来源：
BLOOD | 2024年 / 144卷
关键词：
D O I：
10.1182/blood-2024-211870
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：1438 / 1439
页数：2
相关论文
共 50 条
  • [21] Prevalence of leukoencephalopathy in children treated for acute lymphoblastic leukemia with high-dose methotrexate
    Reddick, WE
    Glass, JO
    Helton, KJ
    Langston, JW
    Xiong, XP
    Wu, SJ
    Pui, CH
    AMERICAN JOURNAL OF NEURORADIOLOGY, 2005, 26 (05) : 1263 - 1269
  • [22] SIDE EFFECTS OF HIGH-DOSE METHOTREXATE TREATMENT TO CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
    Zhou, M.
    Jiang, Y.
    PEDIATRIC BLOOD & CANCER, 2013, 60 : 213 - 213
  • [23] PHARMACOKINETICS OF HIGH-DOSE METHOTREXATE INFUSION IN CHILDREN WITH ACUTE LYMPHOBLASTIC-LEUKEMIA DURING ROUTINE CLINICAL MONITORING
    REGAZZI, MB
    RONDANELLI, R
    MOLINARO, M
    ARICO, M
    PORTA, F
    NESPOLI, L
    EUROPEAN JOURNAL OF PHARMACOLOGY, 1990, 183 (06) : 2300 - 2301
  • [24] High-dose methotrexate in the treatment of adult acute lymphoblastic leukemia
    Gokbuget, N
    Hoelzer, D
    ANNALS OF HEMATOLOGY, 1996, 72 (04) : 194 - 201
  • [25] CLINICAL DOCUMENTATION OF CONSTIPATION IS ASSOCIATED WITH DELAYED CLEARANCE OF HIGH-DOSE METHOTREXATE IN CHILDREN WITH ACUTE LYMPHOBLASTIC LEUKEMIA
    Chavana, Ashley
    Sim, Alex
    Banerjee, Ankona
    Zobeck, Mark
    Gramatges, Monica
    Schafer, Eric
    Scheurer, Michael
    Lupo, Philip
    Rabin, Karen
    Brown, Austin
    Bernhardt, Melanie
    PEDIATRIC BLOOD & CANCER, 2023, 70 : S471 - S471
  • [26] Efficacy and association analysis of high-dose methotrexate in the treatment of children with acute lymphoblastic leukemia
    Gong, Fangwei
    Meng, Qingjun
    Liu, Chengjuan
    Zhao, Yeqi
    ONCOLOGY LETTERS, 2019, 17 (05) : 4423 - 4428
  • [27] High-dose methotrexate and asparaginase for the treatment of children with acute lymphoblastic leukemia: Why and how?
    Kamen, BA
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2004, 26 (06) : 333 - 335
  • [28] Methotrexate-induced Acute Myelopathy in a Teenager With High-risk Acute Lymphoblastic Leukemia
    Geurten, Claire
    Forget, Patricia
    Leroy, Patricia
    Barrea, Christophe
    Hoyoux, Claire
    JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY, 2020, 42 (04) : E262 - E264
  • [29] HIGH-DOSE CYTOSINE-ARABINOSIDE FOR THE TREATMENT OF REFRACTORY ACUTE LYMPHOBLASTIC-LEUKEMIA IN HIGH-RISK PATIENTS
    HERZIG, R
    HERZIG, G
    ADELSTEIN, D
    LAZARUS, H
    PHILLIPS, G
    WOLFF, S
    HINES, J
    CARTER, S
    SPITZER, T
    CLINICAL RESEARCH, 1983, 31 (04): : A778 - A778
  • [30] High dose methotrexate in the treatment of children with acute lymphoblastic leukemia
    Lukito, Johannes Bondan
    PAEDIATRICA INDONESIANA, 2007, 47 (01) : 1 - 6
12345