An overview of the most used synthetic pathways of 1,2,4-triazolo[1,5-a] pyrimidines

被引：1

作者：

Zedan, Mohamed N. ^{[1
]}

Shoman, Mai E. ^{[2
]}

Abdel-Aziz, Mohamed ^{[2
]}

Abdel-Rahman, Hamdy M. ^{[3
,4
]}

机构：

[1] Portsaid Univ, Fac Pharm, Dept Pharmaceut Organ Chem, Portsaid 42526, Egypt

[2] Minia Univ, Fac Pharm, Dept Med Chem, Al Minya 61519, Egypt

[3] Assiut Univ, Fac Pharm, Dept Med Chem, Assiut 71526, Egypt

[4] Badr Univ Assiut BUA, Fac Pharm, Dept Pharmaceut Chem, Assiut 2014101, Egypt

来源：

RESULTS IN CHEMISTRY | 2024年 / 12卷

关键词：

3(5)-Amino-1; 2; 4-triazole (AT); Pyrimidine; Synthesis; BEARING BRIDGEHEAD NITROGEN; DIHYDROOROTATE DEHYDROGENASE INHIBITORS; MICROWAVE-ASSISTED SYNTHESIS; BIOLOGICAL EVALUATION; PART; POTENT; TRIAZOLOPYRIMIDINE; DESIGN; AGENTS; CYCLOCONDENSATION;

D O I：

10.1016/j.rechem.2024.101903

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Among the all possible isomers of triazolopyrimidines, 1,2,4-triazolo[1,5-a]pyrimidines are the most important isomers owing to their vast activities in agriculture and medicinal chemistry. Herein, we present an overview of the most used synthetic pathways of this scaffold to assist researchers design new drug molecules with expected pharmacological activities

引用

页数：17

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