Efficacy and safety of BLV monotherapy for chronic hepatitis delta: posttreatment results through 48 weeks after the end of treatment from an interim analysis of a randomised Phase 3 study MYR301

被引：0

作者：

Aleman, S. ^{[1
]}

Brunetto, M. ^{[2
,3
]}

Blank, A. ^{[4
]}

Andreone, P. ^{[5
]}

Bogomolov, P. ^{[6
]}

Chulanov, V. ^{[7
]}

Mamonova, N. ^{[8
]}

Geyvandova, N. ^{[9
]}

Morozov, V. ^{[10
]}

Sagalova, O. ^{[11
]}

Stepanova, T. ^{[12
]}

Chee, G. M. ^{[13
]}

Mercier, R. C. ^{[13
]}

Lichtman, A. ^{[13
]}

Manuilov, D. ^{[13
]}

Arterburn, S. ^{[13
]}

Lau, A. H. ^{[13
]}

Osinusi, A. ^{[13
]}

Christian-Cox, Flo. ^{[13
]}

Duff, F. ^{[13
]}

zur Wiesch, J. Schulze ^{[14
]}

Cornberg, M. ^{[15
]}

Zeuzem, S. ^{[16
]}

Wedemeyer, H. ^{[15
]}

Lampertico, P. ^{[17
,18
]}

机构：

[1] Karolinska Inst, Karolinska Univ Hosp, Dept Infect Dis, Stockholm, Sweden

[2] Univ Hosp Pisa, Reference Ctr Tuscany Reg Chron Liver Dis & Canc, Hepatol Unit, Pisa, Italy

[3] Univ Pisa, Dept Clin & Expt Med, Pisa, Italy

[4] Heidelberg Univ, Heidelberg Univ Hosp, Med Fac Heidelberg, Internal Med Dept Clin Pharmacol & Pharmacoepidemi, Heidelberg, Germany

[5] Univ Modena & Reggio Emilia, Baggiovara Hosp, Internal Med, Modena, Italy

[6] MF Vladimirsky Moscow Reg Res & Clin Inst, Moscow, Russia

[7] Sechenov Univ, Moscow, Russia

[8] Minist Hlth Russian Federat, FSBI Natl Res Med Ctr Phthisiopulmonol & Infect Di, Moscow, Russia

[9] Stavropol Reg Hosp, Stavropol, Russia

[10] LLC Med Co Hepatolog, Samara, Russia

[11] South Ural State Med Univ, Chelyabinsk, Russia

[12] LLC Clin Modern Med, Moscow, Russia

[13] Gilead Sci Inc, Foster City, CA USA

[14] Univ Hosp Hamburg Eppendorf, Med Microbiol, Hamburg, Germany

[15] Hannover Med Sch, Clin Gastroenterol Hepatol Infect Dis & Endocrinol, Hannover, Germany

[16] Goethe Univ, Univ Hosp, Dept Nucl Med, Frankfurt, Germany

[17] Fdn IRCCS Ca Granda Osped Maggiore Policlin, Div Gastroenterol & Hepatol, Milan, Italy

[18] Univ Milan, CRC A M&A Migliavacca Ctr Liver Dis, Dept Pathophysiol & Transplantat, Milan, Italy

来源：

DIGESTIVE AND LIVER DISEASE | 2025年 / 57卷

关键词：

D O I：

10.1016/j.dld.2025.01.109

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

P-69

引用

页数：2

共 47 条

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Lim, Seng Gee
Pojoga, Cristina
Janssen, Harry
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Janczewska, Ewa
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[32] Efficacy and safety of bepirovirsen in patients with chronic hepatitis B virus infection on stable nucleos (t)ide analogue therapy: interim results from the randomised phase 2b B-Clear study
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Gusev, Denis
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JOURNAL OF HEPATOLOGY, 2022, 77 : S13 - S13
[33] A phase 3 study comparing switching from tenofovir disoproxil fumarate to tenofovir alafenamide with continued TDF treatment in virologically-suppressed patients with chronic hepatitis B (CHB): week 48 efficacy and safety results
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JOURNAL OF HEPATOLOGY, 2019, 70 (01) : E470 - E471
[34] EFFICACY AND SAFETY OF BULEVIRTIDE IN COMBINATION WITH PEGYLATED INTERFERON ALFA-2a IN PATIENTS WITH CHRONIC HEPATITIS DELTA: PRIMARY ENDPOINT RESULTS FROM A PHASE 2b OPEN-LABEL, RANDOMIZED, MULTICENTER STUDY MYR204
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Chulanov, Vladimir
Syutkin, Vladimir E.
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HEPATOLOGY, 2024, 79 (02) : E43 - E44
[35] Efficacy and safety of bulevirtide in combination with pegylated interferon alfa-2a in patients with chronic hepatitis delta: Primary endpoint results from the phase 2b, open-label, randomized, multicenter study MYR204
Asselah, Tarik
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[36] A PHASE 3 STUDY COMPARING SWITCHING FROM TENOFOVIR DISOPROXIL FUMARATE (TDF) TO TENOFOVIR ALAFENAMIDE (TAF) WITH CONTINUED TDF TREATMENT IN VIROLOGICALLY-SUPPRESSED PATIENTS WITH CHRONIC HEPATITIS B (CHB): WEEK 48 EFFICACY AND SAFETY RESULTS
Chan, Henry Lik Yuen
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Buti, Maria
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GUT, 2019, 68 : A142 - A143
[37] Integrated safety analysis of 24-week data from three phase 2 and one phase 3 clinical trials of bulevirtide monotherapy given at 2 mg and 10 mg dose level for treatment of chronic hepatitis delta
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[38] Integrated efficacy analysis of 24-week data from two phase 2 and one phase 3 clinical trials of bulevirtide monotherapy given at 2 mg or 10 mg dose level for treatment of chronic hepatitis delta
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Sagalova, Olga
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Suri, Vithika
Manuilov, Dmitry
Ye, Lei
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JOURNAL OF HEPATOLOGY, 2022, 77 : S828 - S828
[39] Efficacy and safety of glecaprevir/pibrentasvir treatment for 8 weeks in treatment-naive patients with chronic hepatitis C virus infection without cirrhosis or with compensated cirrhosis: Analysis of data pooled from phase 2 and 3 studies
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JOURNAL OF HEPATOLOGY, 2019, 70 (01) : E251 - E251
[40] EFFICACY AND SAFETY OF GLECAPREVIR/PIBRENTASVIR TREATMENT FOR 8 WEEKS IN TREATMENT-NAIVE PATIENTS WITH CHRONIC HEPATITIS C VIRUS INFECTION WITHOUT CIRRHOSIS OR WITH COMPENSATED CIRRHOSIS: ANALYSIS OF DATA POOLED FROM PHASE 2 AND 3 STUDIES
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