Chiral Sodium Glycerophosphate Catalyst for Enantioselective Michael Reactions of Chalcones

被引：0

作者：

Ghigo, Giovanni ^{[1
]}

Rivella, Julia ^{[1
]}

Bose, Alessio Robiolio ^{[1
]}

Dughera, Stefano ^{[1
]}

机构：

[1] Univ Torino, Dept Chem, Via Pietro Giuria 7, I-10125 Turin, Italy

来源：

MOLECULES | 2024年 / 29卷 / 19期

关键词：

conjugate addition; organocatalyst; chiral catalyst; DENSITY FUNCTIONALS;

D O I：

10.3390/molecules29194763

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A chiral sodium glycerophosphate is successfully exploited as a catalyst in the Michael addition of methyl malonate to a number of chalcones. The reactions supplied the target adducts in satisfactory yields and good enantiomeric excesses. A tentative computational study is presented, aiming to understand the reaction mechanism.

引用

页数：7

共 50 条

[21] Enantioselective Michael addition reactions in water using a DNA-based catalyst
Li, Yinghao
Wang, Changhao
Jia, Guoqing
Lu, Shengmei
Li, Can
TETRAHEDRON, 2013, 69 (32) : 6585 - 6590
[22] Highly enantioselective Michael addition reactions with new trimeric chiral phase transfer catalysts
Beneto, Arockiam Jesin
Sivamani, Jayaraman
Ashokkumar, Veeramanoharan
Balasaravanan, Rajendiran
Duraimurugan, Kumaraguru
Siva, Ayyanar
NEW JOURNAL OF CHEMISTRY, 2015, 39 (04) : 3098 - 3104
[23] Chiral primary amine thiourea promoted highly enantioselective Michael reactions of isobutylaldehyde with maleimides
Bai, Jian-Fei
Peng, Lin
Wang, Liang-liang
Wang, Li-Xin
Xu, Xiao-Ying
TETRAHEDRON, 2010, 66 (46) : 8928 - 8932
[24] Synthesis of chiral pentacyclo-undecane macrocycles and their use in enantioselective Michael addition reactions
Boyle, GA
Govender, T
Kruger, HG
Maguire, GEM
TETRAHEDRON-ASYMMETRY, 2004, 15 (23) : 3775 - 3781
[25] Superbasic sodium stannate as catalyst for dehydrogenation, Michael addition and transesterification reactions
Zhang, Shu-Guo
Wei, Yu-Dan
Yin, Shuang-Feng
Luo, Sheng-Lian
Au, Chak-Tong
APPLIED CATALYSIS A-GENERAL, 2011, 406 (1-2) : 113 - 118
[26] Organocatalytic enantioselective Michael and hetero-Michael reactions
Vicario, Jose L.
Badia, Dolores
Carrillo, Luisa
SYNTHESIS-STUTTGART, 2007, (14): : 2065 - 2092
[27] A chiral amino-naphthalene-derived prolinamide catalyst for the enantioselective Michael addition of ketones to nitroolefins
Yu, Chuanming
Zhang, Ke
Shi, Xiangjun
JOURNAL OF CHEMICAL RESEARCH, 2012, (05) : 278 - 282
[28] A new polymer-anchored chiral catalyst for asymmetric Michael addition reactions
Sundararajan, G
Prabagaran, N
ORGANIC LETTERS, 2001, 3 (03) : 389 - 392
[29] Chiral pyrrolidine-triazole conjugate catalyst for asymmetric Michael and Aldol reactions
Chandrasekhar, S.
Tiwarl, Bhoopendra
Parida, Bibhuti B.
Reddy, Ch. Raji
TETRAHEDRON-ASYMMETRY, 2008, 19 (04) : 495 - 499
[30] An ATP-Cu(ii) catalyst efficiently catalyzes enantioselective Michael reactions in water
Dong, Xingchen
Yuan, Zijian
Qu, Yao
Gao, Yuxin
Pei, Xue
Qi, Qianqian
Pei, Yujuan
Li, Jiaqi
Chen, Yashao
Wang, Changhao
GREEN CHEMISTRY, 2021, 23 (24) : 9876 - 9880

← 1 2 3 4 5 →