Somatic TP53 mutations (sTP53m) in cell-free circulating DNA (cfDNA) in high-grade serous ovarian cancer (HGSOC)

被引：0
|
作者：
Ramsden, Catherine [1 ]
McDermott, John [1 ,2 ,3 ]
Clamp, Andrew [4 ,5 ]
Hasan, Jurjees [4 ]
Mitchell, Claire [4 ]
Salih, Zena [4 ]
Woodward, Emma [1 ,2 ,3 ]
Evans, Gareth [1 ,2 ,3 ]
Taylor, Stephen [5 ]
Jayson, Gordon [4 ,5 ]
Schlecht, Helene [1 ,2 ]
Burghel, George [1 ,2 ,3 ]
Morgan, Robert [4 ,5 ]
机构：
[1] Manchester Ctr Genom Med, North West Genom Lab Hub, Manchester, Lancs, England
[2] Manchester Univ NHS Fdn Trust, Dept Clin Genet, Manchester, Lancs, England
[3] Univ Manchester, Sch Biol Sci, Div Evolut Infect & Genom, Manchester, Lancs, England
[4] Christie NHS Fdn Trust, Dept Med Oncol, Manchester, Lancs, England
[5] Univ Manchester, Sch Med Sci, Div Canc Sci, Fac Biol Med & Hlth, Manchester, Lancs, England
来源：
EUROPEAN JOURNAL OF HUMAN GENETICS | 2024年 / 32卷
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
P15.034.C
引用
收藏
页码：1599 / 1599
页数：1
相关论文
共 50 条
  • [1] TP53 Mutations in Circulating Cell-Free DNA as Longitudinal Biomarker for High-Grade Serous Ovarian Cancer
    Vitale, S. R.
    Groenendijk, F. H.
    Beaufort, C.
    Helmijr, J.
    Dubbink, H. J.
    Atmodimedjo, P.
    van Marion, R.
    Dinjens, W. N. M.
    Ewing-Graham, P. C.
    van Doorn, H. C.
    Berns, E. M. J. J.
    Boere, I. A.
    Helleman, J.
    Jansen, M.
    JOURNAL OF MOLECULAR DIAGNOSTICS, 2018, 20 (03): : S10 - S11
  • [2] TP53 Mutations in Serum Circulating Cell-Free Tumor DNA As Longitudinal Biomarker for High-Grade Serous Ovarian Cancer
    Vitale, Silvia R.
    Groenendijk, Floris H.
    van Marion, Ronald
    Beaufort, Corine M.
    Helmijr, Jean C.
    Dubbink, Hendrikus Jan
    Dinjens, Winand N. M.
    Ewing-Graham, Patricia C.
    Smolders, Ramon
    van Doorn, Helena C.
    Boere, Ingrid A.
    Berns, Els M. J. J.
    Helleman, Jozien
    Jansen, Maurice P. H. M.
    BIOMOLECULES, 2020, 10 (03)
  • [3] Circulating TP53 mutations as a biomarker of high-grade serous cancer
    Christie, Elizabeth
    Hunter, Tane
    Bowtell, David
    CLINICAL CANCER RESEARCH, 2015, 21
  • [4] Detection of Somatic TP53 Mutations in Tampons of Patients With High-Grade Serous Ovarian Cancer
    Erickson, Britt K.
    Kinde, Isaac
    Dobbin, Zachary C.
    Wang, Yuxuan
    Martin, Jovana Y.
    Alvarez, Ronald D.
    Conner, Michael G.
    Huh, Warner K.
    Roden, Richard B. S.
    Kinzler, Kenneth W.
    Papadopoulos, Nickolas
    Vogelstein, Bert
    Diaz, Luis A., Jr.
    Landen, Charles N., Jr.
    OBSTETRICS AND GYNECOLOGY, 2014, 124 (05): : 881 - 885
  • [5] High-grade serous Ovarian Cancer: TP53 Mutations and Platinum Response
    Lorenz, Judith
    GEBURTSHILFE UND FRAUENHEILKUNDE, 2024, 84 (07)
  • [6] TP53 mutations on circulating cell-free DNA
    Pantel, Klaus
    EBIOMEDICINE, 2016, 10 : 15 - +
  • [7] TP53 mutations as a biomarker for high-grade serous ovarian cancer: are we there yet?
    Oien, Derek B.
    Chien, Jeremy
    TRANSLATIONAL CANCER RESEARCH, 2016, 5 : S264 - S268
  • [8] Identification of Novel Somatic TP53 Mutations in Patients with High-Grade Serous Ovarian Cancer (HGSOC) Using Next-Generation Sequencing (NGS)
    Garziera, Marica
    Cecchin, Erika
    Canzonieri, Vincenzo
    Sorio, Roberto
    Giorda, Giorgio
    Scalone, Simona
    De Mattia, Elena
    Roncato, Rossana
    Gagno, Sara
    Poletto, Elena
    Romanato, Loredana
    Sartor, Franca
    Polesel, Jerry
    Toffoli, Giuseppe
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2018, 19 (05)
  • [9] Clinical relevance of TP53 hotspot mutations in high-grade serous ovarian cancers
    Tuna, Musaffe
    Ju, Zhenlin
    Yoshihara, Kosuke
    Amos, Christopher I.
    Tanyi, Janos L.
    Mills, Gordon B.
    BRITISH JOURNAL OF CANCER, 2020, 122 (03) : 405 - 412
  • [10] The effect of germline polymorphisms on somatic hotspot mutations in TP53 for the treatment of high-grade serous ovarian carcinoma
    De Souza, Cristabelle Madona N.
    CANCER RESEARCH, 2018, 78 (13)
12345