Senolytic Treatment Attenuates Palmitic Acid-Induced Microglial Activation: Therapeutic Implications for Obesity-Induced Sympathoexcitation

被引:0
|
作者
Plakkot, Bhuvana
Turtle, Chenoa
Subramanian, Madhan
机构
关键词
D O I
10.1161/hyp.81.suppl_1.P162
中图分类号
R6 [外科学];
学科分类号
1002 ; 100210 ;
摘要
P162
引用
收藏
页数:2
相关论文
共 50 条
  • [21] 5-ALA Attenuates the Palmitic Acid-Induced ER Stress and Apoptosis in Bovine Mammary Epithelial Cells
    Sharmin, Mst Mamuna
    Islam, Md Aminul
    Yamamoto, Itsuki
    Taniguchi, Shin
    Yonekura, Shinichi
    MOLECULES, 2021, 26 (04):
  • [22] Kainic acid-induced microglial activation is attenuated in aged interleukin-18 deficient mice
    Xing-Mei Zhang
    Tao Jin
    Hernan Concha Quezada
    Eilhard Mix
    Bengt Winblad
    Jie Zhu
    Journal of Neuroinflammation, 7
  • [23] Obesity-induced hypogonadism: Pathophysiological roles of a novel hypothalamic miRNA/Kisspeptin pathway and potential therapeutic implications
    Soledad Avendano, Ma
    Perdices Lopez, Cecilia
    Jesus Vazquez, Ma
    Barroso, Alexia
    Ruiz Pino, Francisco
    Antonio Calzado, Marco
    Manuel Castellano, Juan
    Ma Briones, Ana
    Tena Sempere, Manuel
    BASIC & CLINICAL PHARMACOLOGY & TOXICOLOGY, 2019, 125 : 37 - 38
  • [24] Bortezomib attenuates palmitic acid-induced ER stress, inflammation and insulin resistance in myotubes via AMPK dependent mechanism
    Kwak, Hyun Jeong
    Choi, Hye-Eun
    Jang, Jinsun
    Park, Soo Kyung
    Bae, Young-An
    Cheon, Hyae Gyeong
    CELLULAR SIGNALLING, 2016, 28 (08) : 788 - 797
  • [25] Increasing Surface Expression of Pancreatic β cell-KATP Channels Attenuates Palmitic acid-induced Lipotoxicity in vivo and in vitro
    Chen, Pei-Chun
    Ruan, Jing-Syuna
    Kuo, Yi-Ying
    Chao, Ru-Yi
    Chen, Yun-Wen
    FASEB JOURNAL, 2018, 32 (01):
  • [26] Delayed Treatment with Isoflurane Attenuates Lipopolysaccharide and Interferon γ-induced Activation and Injury of Mouse Microglial Cells
    Kim, Jie-Ae
    Li, Liaoliao
    Zuo, Zhiyi
    ANESTHESIOLOGY, 2009, 111 (03) : 566 - 573
  • [27] Microglial activation by epileptic activities through the propagation pathway of kainic acid-induced hippocampal seizures in the rat
    Taniwaki, Y
    Kato, M
    Araki, T
    Kobayashi, T
    NEUROSCIENCE LETTERS, 1996, 217 (01) : 29 - 32
  • [28] Research Kainic acid-induced microglial activation is attenuated in aged interleukin-18 deficient mice
    Zhang, Xing-Mei
    Jin, Tao
    Quezada, Hernan Concha
    Mix, Eilhard
    Winblad, Bengt
    Zhu, Jie
    JOURNAL OF NEUROINFLAMMATION, 2010, 7
  • [29] Treatment of cigarette smoke extract and condensate differentially potentiates palmitic acid-induced lipotoxicity and steatohepatitis in vitro
    Zhou, Zixiong
    Kim, Jong Won
    Zhao, Jing
    Qi, Jing
    Choi, Seong Jin
    Lim, Chae Woong
    Lee, Moo-Yeol
    Lee, Kyuhong
    Kim, Bumseok
    TOXICOLOGY IN VITRO, 2018, 52 : 33 - 40
  • [30] Silencing MicroRNA-155 Attenuates Kainic Acid-Induced Seizure by Inhibiting Microglia Activation
    Fu, Huajun
    Cheng, Yiyun
    Luo, Haijuan
    Rong, Zhouyi
    Li, Yanfang
    Lu, Ping
    Ye, Xiaowen
    Huang, Weiyan
    Qi, Ziguo
    Li, Xiuying
    Cheng, Baoying
    Wang, Xintian
    Yao, Yi
    Zhang, Yun-Wu
    Zheng, Weihong
    Zheng, Honghua
    NEUROIMMUNOMODULATION, 2019, 26 (02) : 67 - 76