The Efficacy for Hypertensive Intracerebral Hemorrhage Between Neuroendoscopic Surgery and Conservative Treatment A Retrospective Observational

被引:0
|
作者
Huo, Guojin [1 ]
Lan, Yanping [2 ]
Feng, Yi [1 ]
Gao, Xiang [1 ]
Chen, Chen [1 ]
机构
[1] Yulin 1 Hosp, Dept Neurosurg, Yulin City 719000, Shaanxi, Peoples R China
[2] Peoples Hosp Ningxia Hui Autonomous Reg, Dept Neurosurg, Yinchuan City, Ningxia, Peoples R China
关键词
neuroendoscopic surgery; hypertensive intracerebral hemorrhage; inflammatory response; neurological function; therapeutic effects; retrospective observation; QUALITY-OF-LIFE; OPERATION TIME; BLOOD-PRESSURE; MANAGEMENT; ALPHA; SERUM;
D O I
10.1097/NRL.0000000000000597
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
Objectives: This study aims to investigate the efficacy of neuro-endoscopic surgery in the treatment of hypertensive intracerebral hemorrhage (HICH). Methods: A total of 193 patients diagnosed with HICH were divided into 2 groups in this study: the observation group (n= 101) received neuroendoscopic surgery, whereas the control group (n= 92) underwent conservative treatment. Then, the outcomes between these 2 groups were compared and assessed. Results: In the pretreatment phase, there were no significant differences in the levels of inflammation and neurological function scores between these 2 groups (P> 0.05). After 3 months of treatment, the observation group displayed significantly shorter median hospital stay, lower average hospital costs, and faster hematoma resorption time, along with reduced levels of tumor necrosis factoralpha (TNF-a), C-reactive protein (CRP), interleukin (IL)-6 and IL8, aquaporin-4 (AQP4), macrophage migration inhibitory factor (MIF), matrix metalloproteinase-9 (MMP-9), granulocyte macrophage colony stimulating factor (GM-CSF), Nerve Deficiency Scale (NDS), Graeb score, and national institute of health stroke scale (NIHSS) compared with the control group (P< 0.05). In addition, the observation group exhibited higher rate of hematoma clearance and better glasgow outcome scale (GOS) score compared with the control group (P< 0.05). The effective treatment rate in the observation group was notably superior to that in the control group (89.11% vs. 73.91%, P< 0.05). Conclusions: Neuroendoscopic surgery is an effective treatment for HICH, with alleviating the inflammatory response and enhancing the neurological function. The treatment shows promising outcomes and justifies extensive implementation.
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收藏
页码:109 / 115
页数:7
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