Risk Factors for Renal Involvement in Childhood Henoch-Schonlein Purpura (IgA Vasculitis)

被引：0
|
作者：
Min, Shuhui [1 ]
Chen, Xi [1 ]
Wang, Danfeng [1 ]
Lin, Xiao [1 ]
Jiang, Guan [1 ]
机构：
[1] Xuzhou Med Univ, Dept Dermatol, Affiliated Hosp, Xuzhou, Jiangsu, Peoples R China
来源：
JCPSP-JOURNAL OF THE COLLEGE OF PHYSICIANS AND SURGEONS PAKISTAN | 2024年 / 34卷 / 10期
关键词：
Henoch-schonlein purpura; Immunoglobulin A vasculitis; Nephritis; D-dimer; Risk factors;
D O I：
10.29271/jcpsp.2024.10.1258
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
This study was designed to investigate the risk factors for renal involvement in children with immunoglobulin A (IgA) vasculitis. It is a hospital-based retrospective cohort study with a sample size of 117 children aged <= 16 years with primary IgA vasculitis. Out of 117 patients, 49 (41.9%) developed renal injury. Univariate analysis revealed that age, gastrointestinal bleeding (GIB), time of duration, white blood cell count, D-dimer, and platelet count were all associated with renal injury in the patients with HSP. These variables were included in the multivariate logistic regression analysis. Results showed that elevated D-dimer level, older age, and GIB were independent risk factors for renal damage in patients with IgA vasculitis.
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收藏
页码：1258 / 1261
页数：4
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