Acute Kidney Disease in Oncology: A New Concept to Enhance the Understanding of the Impact of Kidney Injury in Patients with Cancer

被引：1

作者：

Floris, Matteo ^{[1
]}

Trevisani, Francesco ^{[2
]}

Angioi, Andrea ^{[1
]}

Lepori, Nicola ^{[1
,3
]}

Simeoni, Mariadelina ^{[4
]}

Cabiddu, Gianfranca ^{[1
,3
]}

Pani, Antonello ^{[1
,3
]}

Rosner, Mitchell Howard ^{[5
]}

机构：

[1] Univ Cagliari, G Brotzu Hosp, Nephrol Dialysis & Transplantat Unit, Cagliari, Italy

[2] IRCCS San Raffaele Sci Inst, Urol Res Inst URI, Div Expt Oncol, Milan, Italy

[3] Univ Cagliari, Med Sci Dept, Cagliari, Italy

[4] Univ Campania Luigi Vanvitelli, Dept Translat Med Sci, Naples, Italy

[5] Univ Virginia Hlth Syst, Div Nephrol, Charlottesville, VA USA

来源：

KIDNEY & BLOOD PRESSURE RESEARCH | 2024年 / 49卷 / 01期

关键词：

Acute kidney disease; Acute kidney injury; Anticancer therapy; Immunotherapy; Cancer; Toxicity; Onconephrology; DEFINITION; OUTCOMES;

D O I：

10.1159/000540908

中图分类号：

Q4 [生理学];

学科分类号：

071003 ;

摘要：

Background: Cancer patients are prone to developing acute kidney disease (AKD), yet this phenomenon remains understudied compared to acute kidney injury (AKI). AKD, which often develops insidiously, can cause treatment interruptions, extended hospital stays, and increased mortality. Summary: This perspective article explores the intricate relationship between AKD and cancer, focusing on prevalence, risk factors, implications for anticancer therapy, and long-term outcomes, including chronic kidney disease progression. Key Messages: To emphasize the importance of early detection and intervention, this work advocates for increased research and awareness among clinicians to improve patient outcomes and manage healthcare burdens associated with AKD in cancer patients. (c) 2024 The Author(s). Published by S. Karger AG, Basel

引用

页码：753 / 760

页数：8

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