Primary Hodgkin's lymphoma of stomach: A case report with literature review

The gastrointestinal (GI) tract is the commonest site of extranodal lymphoma, and the stomach is the most frequent site for extranodal GI lymphoma (60%). Primary gastric lymphoma (PGL) is relatively rare, but the incidence of the disease is increasing. About 90% of primary gastric lymphoma is non-Hodgkin type (NHL), either mucosal-associated lymphoid tissue lymphoma or diffuse large B-cell lymphoma. In contrast, primary Hodgkin's lymphoma (HL) is very rare. Until now, a handful of cases have been reported in the literature. It poses a great challenge in diagnosis due to its rarity and nonspecific GI symptoms like other diseases. Hence, clinicians and pathologists must understand the clinical symptoms and diagnostic workup to treat these lymphomas properly. Here, we report a case of primary HL, which was misdiagnosed as carcinoma stomach with gastric outlet obstruction and was established on histopathology with follow-up immunohistochemistry.