Sustained Patient Meaningful Outcomes of Pain and Fatigue Relief and Improved Physical Functioning with Filgotinib in Rheumatoid Arthritis: A Post Hoc Analysis

被引:0
|
作者
Alten, Rieke [1 ]
Fautrel, Bruno [2 ,3 ]
Conaghan, Philip G. [4 ,5 ]
de Vries, Dick [6 ]
Faes, Margaux [7 ]
Piovesan, Mercedes [8 ]
Van Beneden, Katrien [9 ]
Watson, Chris [10 ]
Weel-Koenders, Angelique E. A. M. [11 ,12 ]
Feist, Eugen [13 ]
de Vlam, Kurt [14 ,15 ]
机构
[1] Univ Med Berlin, Dept Internal Med & Rheumatol, Schlosspark Klin, Berlin, Germany
[2] Inst Pierre Louis Epidemiol & Sante Publ, INSERM, UMRS 1136, Paris, Ile De France, France
[3] Sorbonne Univ, Hop Pitie Salpetriere, Assistance Publ Hop Paris, Dept Rhumatol, Paris, Ile De France, France
[4] Univ Leeds, Leeds Inst Rheumat & Musculoskeletal Med, Leeds, England
[5] Leeds Teaching Hosp NHS Trust, NIHR Leeds Biomed Res Ctr, Leeds, England
[6] Galapagos BV, Clin Dev, Leiden, Netherlands
[7] Galapagos NV, Biostat, Mechelen, Belgium
[8] Galapagos Biopharma Spain SLU, Med Affairs, Madrid, Spain
[9] Galapagos NV, Med Affairs, Mechelen, Belgium
[10] Galapagos Biotech Ltd, Med Affairs, Cambridge, England
[11] Erasmus Univ, Erasmus Sch Hlth Policy & Management, Rotterdam, Netherlands
[12] Maasstad Hosp, Dept Rheumatol & Clin Immunol, Rotterdam, Netherlands
[13] Otto von Guericke Univ, Helios Clin Vogelsang Gommern, Department Rheumatol, Gommern, Germany
[14] UZ Leuven, Dept Rheumatol, Leuven, Belgium
[15] Katholieke Univ Leuven, Dept Dev & Regenerat, Skeletal Biol & Engn Res Ctr, Leuven, Belgium
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
0518
引用
收藏
页码:1052 / 1055
页数:4
相关论文
共 50 条
  • [11] Meaningful Change Thresholds for Patient-Reported Outcomes Measurement Information System (PROMIS) Fatigue and Pain Interference Scores in Patients With Rheumatoid Arthritis
    Beaumont, Jennifer L.
    Davis, Elizabeth S.
    Curtis, Jeffrey R.
    Cella, David
    Yun, Huifeng
    JOURNAL OF RHEUMATOLOGY, 2021, 48 (08) : 1239 - 1242
  • [12] Long-term Clinical Profile of Filgotinib in Patients with Rheumatoid Arthritis by Cardiovascular Risk Factors: A Post Hoc Subgroup Analysis
    Buch, Maya
    Gomez-Puerta, Jose A.
    Burmester, Gerd
    Combe, Bernard G.
    Rajendran, Vijay
    Stiers, Pieter-Jan
    Van Hoek, Paul
    Van Beneden, Katrien
    Gottenberg, Jacques-Eric
    Tanaka, Yoshiya
    Aletaha, Daniel
    Westhovens, Rene
    Caporali, Roberto F.
    ARTHRITIS & RHEUMATOLOGY, 2023, 75 : 875 - 877
  • [13] Improvements in physical function and pain relief were sustained in rheumatoid arthritis patients treated for 2 years with certolizumab pegol
    Mease, Philip
    Coteur, Geoffiroy
    Keininger, Dorothy L.
    ARTHRITIS AND RHEUMATISM, 2008, 58 (09): : S528 - S529
  • [14] Improvements in Physical Function and Pain Relief Were Sustained in Rheumatoid Arthritis Patients Treated for 2 Years with Certolizumab Pegol
    Bykerk, Vivian
    Mease, Philip
    Coteur, Geoffroy
    Keininger, Dorothy
    JOURNAL OF RHEUMATOLOGY, 2009, 36 (11) : 2567 - 2567
  • [15] Filgotinib Demonstrates Efficacy in Rheumatoid Arthritis Independent of Smoking Status: Post Hoc Analysis of Phase 3 Trials and Claims-Based Analysis
    Jeffrey R. Curtis
    Paul Emery
    Bryan Downie
    Yan Zhong
    Jinfeng Liu
    Ling Han
    Rachael E. Hawtin
    Gerd Rüdiger Burmester
    Rheumatology and Therapy, 2024, 11 : 177 - 189
  • [16] Filgotinib Demonstrates Efficacy in Rheumatoid Arthritis Independent of Smoking Status: Post Hoc Analysis of Phase 3 Trials and Claims-Based Analysis
    Curtis, Jeffrey R.
    Emery, Paul
    Downie, Bryan
    Zhong, Yan
    Liu, Jinfeng
    Han, Ling
    Hawtin, Rachael E.
    Burmester, Gerd Ruediger
    RHEUMATOLOGY AND THERAPY, 2024, 11 (01) : 177 - 189
  • [17] Efficacy and safety of filgotinib in methotrexate-naive patients with rheumatoid arthritis with poor prognostic factors: post hoc analysis of FINCH 3
    Aletaha, Daniel
    Westhovens, Rene
    Gaujoux-Viala, Cecile
    Adami, Giovanni
    Matsumoto, Alan
    Bird, Paul
    Messina, Osvaldo Daniel
    Buch, Maya H.
    Bartok, Beatrix
    Yin, Zhaoyu
    Guo, Ying
    Hendrikx, Thijs
    Burmester, Gerd R.
    RMD OPEN, 2021, 7 (02):
  • [18] Low Patient Global Assessment Scores in Rheumatoid Arthritis Are Associated with Pain and Physical Function in Patients Treated with Tofacitinib: A Post-Hoc Analysis of Phase 3 Trials
    Strand, Vibeke
    Alten, Rieke
    Kaine, Jeffrey
    Soonasra, Arif
    Murray, Christopher W.
    Fan, Haiyun
    Mojcik, Christopher F.
    Wallenstein, Gene
    ARTHRITIS & RHEUMATOLOGY, 2017, 69
  • [19] Correlation of pain relief with physical function in hand osteoarthritis: randomized controlled trial post hoc analysis
    Barthel, H. Richard
    Peniston, John H.
    Clark, Michael B.
    Gold, Morris S.
    Altman, Roy D.
    ARTHRITIS RESEARCH & THERAPY, 2010, 12 (01)
  • [20] Filgotinib Provided Rapid and Sustained Improvements in Functional Status, Pain, Health-related Quality of Life, and Fatigue in Patients with Rheumatoid Arthritis and Inadequate Response to Methotrexate
    Kivitz, Alan
    Tanaka, Yoshiya
    Lee, Susan
    Ye, Lei
    Hu, Hao
    Besuyen, Robin
    Combe, Bernard
    ARTHRITIS & RHEUMATOLOGY, 2020, 72