Impact of COVID-19 infection on lung function and nutritional status amongst individuals with cystic fibrosis: A global cohort study

被引：0

作者：

Semenchuk, Julie ^{[1
]}

Naito, Yumi ^{[2
]}

Charman, Susan C. ^{[2
]}

Carr, Siobhan B. ^{[3
,4
]}

Cheng, Stephanie Y. ^{[5
]}

Marshall, Bruce C. ^{[6
]}

Faro, Albert ^{[6
]}

Elbert, Alexander ^{[6
]}

Gutierrez, Hector H. ^{[7
]}

Goss, Christopher H. ^{[8
]}

Karadag, Bulent ^{[9
]}

Burgel, Pierre-Regis ^{[10
,11
]}

Colombo, Carla ^{[12
]}

Salvatore, Marco ^{[13
,14
]}

Padoan, Rita ^{[15
]}

Daneau, Geraldine ^{[16
]}

Harutyunyan, Satenik ^{[17
]}

Kashirskaya, Nataliya ^{[18
]}

Kirwan, Laura ^{[19
]}

Middleton, Peter G. ^{[20
]}

Ruseckaite, Rasa ^{[21
]}

de Monestrol, Isabelle ^{[22
]}

Naehrlich, Lutz ^{[23
]}

Mondejar-Lopez, Pedro ^{[24
]}

Jung, Andreas ^{[25
]}

van Rens, Jacqui ^{[26
]}

Bakkeheim, Egil ^{[27
]}

Orenti, Annalisa ^{[28
]}

Ommen, Domenique Zomer-van ^{[29
]}

da Silva-Filho, Luiz Vicente R. F. ^{[30
]}

Fernandes, Flavia Fonseca ^{[31
,32
]}

Zampoli, Marco ^{[33
]}

Stephenson, Anne L. ^{[1
]}

机构：

[1] St Michaels Hosp, Dept Respirol, Toronto, ON, Canada

[2] UK Trust, London, England

[3] Royal Brompton & Harefield Hosp, Guys & St Thomass NHS Fdn Trust, London, England

[4] Imperial Coll, London, England

[5] Cyst Fibrosis Canada, Toronto, ON, Canada

[6] Cyst Fibrosis Fdn, Bethesda, MD USA

[7] Univ Alabama Birmingham, Div Pediat Pulm & Sleep Med, Birmingham, AL USA

[8] Univ Washington, Dept Med, Div Pulm Crit Care & Sleep Med, Med Ctr, Seattle, WA USA

[9] Marmara Univ, Fac Med, Div Pediat Pulmonol, Istanbul, Turkiye

[10] Cochin Hosp, APHP, Natl Reference CF Ctr & Resp Med, Paris, France

[11] Univ Paris Cite, Inst Cochin InsermU1016, Paris, France

[12] Univ Milan, Fdn IRCCS CaGranda Osped Maggiore Policlin, Milan, Italy

[13] Natl Ctr Rare Dis, Undiagnosed Rare Dis Interdept Unit, Rome, Italy

[14] Ist Super Sanita, Italian CF, Rome, Italy

[15] Italian Cyst Fibrosis Registry, Sci Board, Rome, Italy

[16] Yerevan Univ, Muratsan Hosp, CF Ctr, Yerevan, Armenia

[17] Belgian Cyst Fibrosis Registry, Dept epidemiol & publ Hlth, Hlth Serv Res, Sciensano, Belgium

[18] Moscow Reg Res & Clin Inst MONIKI, Res Ctr Med Genet, Moscow, Russia

[19] Univ Coll Dublin, Cyst Fibrosis Registry Ireland, Woodview House, Dublin, Ireland

[20] Westmead Hosp, Dept Resp & Sleep Med, Bronchiectasis & CF Serv, Sydney, Australia

[21] Monash Univ, Dept Publ Hlth & Prevent Med, Melbourne, Vic, Australia

[22] Karolinska Univ Hosp Huddinge, Karolinska Inst, Stockholm CF Ctr, Dept Pediat, Huddinge, Sweden

[23] Justus Liebig Univ Giessen, Dept Pediat, Giessen, Germany

[24] Hosp Clin Univ Virgen Arrixaca, Murcia, Spain

[25] Univ Childrens Hosp Zurich, Dept Pulmonol, Zurich, Switzerland

[26] Univ Hosp Leuven, Dept Paediat, Leuven, Belgium

[27] Oslo Univ Hosp, Natl Resource Ctr Cyst Fibrosis, Dept Paediat & Adolescent Med, Oslo, Norway

[28] Univ Milan, Dept Clin Sci & Community Hlth, Dipartimento Eccellenza 2023 2027, Lab Med Stat Biometry & Epidemiol G A Maccacaro, Milan, Italy

[29] Dutch CF Fdn NCFS, Baarn, Netherlands

[30] Inst Crianca & Adolescente HCFMUSP, Sao Paulo, Brazil

[31] Univ Fed Catalao, Med Dept, Catalao, Brazil

[32] Hosp Base Dist Fed, Brasilia, Brazil

[33] Univ Cape Town, Red Cross War Mem Childrens Hosp, Dept Paediat & Child Hlth, Cape Town, South Africa

来源：

JOURNAL OF CYSTIC FIBROSIS | 2024年 / 23卷 / 05期

关键词：

COVID-19; Coronavirus; Cystic fibrosis; SARS-COV-2; INFECTION; PEOPLE; CHILDREN;

D O I：

10.1016/j.jcf.2024.07.019

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

Background Factors associated with severe COVID-19 infection have been identified; however, the impact of infection on longer-term outcomes is unclear. The objective of this study was to examine the impact of COVID-19 infection on the trajectory of lung function and nutritional status in people with cystic fibrosis (pwCF). Methods This is a retrospective global cohort study of pwCF who had confirmed COVID-19 infection diagnosed between January 1, 2020 and December 31, 2021. Forced expiratory volume in one second percent predicted (ppFEV(1)) and body mass index (BMI) twelve months prior to and following a diagnosis of COVID-19 were recorded. Change in mean ppFEV(1) and BMI were compared using a t-test. A linear mixed-effects model was used to estimate change over time and to compare the rate of change before and after infection. Results A total of 6,500 cases of COVID-19 in pwCF from 33 countries were included for analysis. The mean difference in ppFEV(1) pre- and post-infection was 1.4 %, (95 % CI 1.1, 1.7). In those not on modulators, the difference in rate of change pre- and post-infection was 1.34 %, (95 % CI -0.88, 3.56) per year (p = 0.24) and -0.74 % (-1.89, 0.41) per year (p = 0.21) for those on elexacaftor/tezacaftor/ivacaftor. No clinically significant change was noted in BMI or BMI percentile before and after COVID-19 infection. Conclusions No clinically meaningful impact on lung function and BMI trajectory in the year following infection with COVID-19 was identified. This work highlights the ability of the global CF community to unify and address critical issues facing pwCF.

引用

页码：815 / 822

页数：8

共 50 条

[11] Impact of telehealth during the COVID-19 pandemic on clinical and nutritional conditions of adolescents with cystic fibrosis
da Silva Reis, Lavinia Mayara
de Cerqueira Pinheiro, Aline Antunes
da Silva Junior, Mauricio Antonio
Goncalves, Christine Pereira
Santana, Nelbe Nesi
JORNAL BRASILEIRO DE PNEUMOLOGIA, 2024, 50 (02)
[12] Clinical and anthropometric evolution of individuals with cystic fibrosis during COVID-19 pandemic: A 24-month cohort study
de Oliveira, Taynara Julia
Altoe, Izabela Dondoni
Arpini, Luana da Silva Baptista
Liberato, Fernanda Mayrink Goncalves
Melotti, Roberta de Cassia Nunes Cruz
Wittmer, Veronica Lourenco
Duarte, Halina
Barbalho-Moulim, Marcela Cangussu
Paro, Flavia Marini
PEDIATRIC PULMONOLOGY, 2024, 59 (07) : 1962 - 1969
[13] Longitudinal trends in nutritional status and the relation between lung function and BMI in cystic fibrosis: a population-based cohort study
Stephenson, Anne L.
Mannik, Lisa A.
Walsh, Shirley
Brotherwood, Michelle
Robert, Ronalee
Darling, Pauline B.
Nisenbaum, Rosane
Moerman, Joost
Stanojevic, Sanja
AMERICAN JOURNAL OF CLINICAL NUTRITION, 2013, 97 (04): : 872 - 877
[14] Preservation of Lung Function Despite Covid-19 Infection in a Cohort of Lung Transplant Recipients
Ennis, S. L.
Levvey, B.
Shingles, H.
Holsworth, L.
Snell, G.
Gardiner, B.
JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2023, 42 (04): : S308 - S308
[15] Does cystic fibrosis constitute an advantage in COVID-19 infection?
Bezzerri, Valentino
Lucca, Francesca
Volpi, Sonia
Cipolli, Marco
ITALIAN JOURNAL OF PEDIATRICS, 2020, 46 (01)
[16] Does cystic fibrosis constitute an advantage in COVID-19 infection?
Valentino Bezzerri
Francesca Lucca
Sonia Volpi
Marco Cipolli
Italian Journal of Pediatrics, 46
[17] Activity levels and the relationship to lung function and nutritional status in children with cystic fibrosis
Boucher, GP
Lands, LC
Hay, JA
Hornby, L
AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION, 1997, 76 (04) : 311 - 315
[18] Lung function and nutritional status in children with cystic fibrosis and primary ciliary dyskinesia
Walker, Woolf
Harris, Amanda
Rubbo, Bruna
Keenan, Victoria
Friend, Amanda
Payne, Sarah
Maddison, Judi
Yonge, Caroline
Crocker, Catherine
McGinnity, Tricia
Curbishley, Teresa
Gove, Kerry
Phillips, Sian
Legg, Julian
Evans, Hazel
Lucas, Jane
Connett, Gary
EUROPEAN RESPIRATORY JOURNAL, 2016, 48
[19] Nutritional status and lung function in children with pancreatic-sufficient cystic fibrosis
Madde, Ankitha
Okoniewski, William
Sanders, Don B.
Ren, Clement L.
Weiner, Daniel J.
Forno, Erick
JOURNAL OF CYSTIC FIBROSIS, 2022, 21 (05) : 769 - 776
[20] A retrospective cohort study on the association between nutritional status and prognosis in COVID-19 patients with severe and critical infection
Gou, Shuangyun
Tang, Dan
Li, Weiyi
Qiu, Yu
Xu, Xiaoping
Yang, Li
Jiang, Li
JOURNAL OF INTERNATIONAL MEDICAL RESEARCH, 2024, 52 (11)

← 1 2 3 4 5 →