Efficacy and safety of larotrectinib in neurotrophic tyrosine receptor kinase fusion-positive solid tumors: A multicenter retrospective cohort study in Korea

被引:0
|
作者
Lee, S. [1 ]
Yoon, S. [2 ]
Choi, W. [3 ]
Jung, H. A. [4 ]
Bae, S. B. [5 ]
Kim, C. G. [6 ]
Kim, H. R. [7 ]
Lee, K-w. [8 ,14 ]
Kang, E. J. [9 ]
Shin, K. [10 ,11 ]
Lim, D-j. [12 ]
Kim, . s.
Park, S. [13 ]
Lee, K-e.
Lee, Y. [15 ]
Kim, H. S. [16 ]
Kim, T. J. [17 ]
Kim, M. J. [18 ]
Kang, J. H. [19 ]
机构
[1] Yonsei Univ, Coll Med, Gangnam Severance Hosp, Div Med Oncol,Dept Internal Med, Seoul, South Korea
[2] Univ Ulsan, Asan Med Ctr, Oncol Dept, Seoul, South Korea
[3] Ctr Clin Trials, Natl Canc Ctr, NCC, Goyang, South Korea
[4] Sungkyunkwan Univ, Dept Med, Samsung Med Ctr SMC, Div Hematol Oncol,Sch Med, Seoul, South Korea
[5] Soonchunhyang Univ Hosp, Dept Internal Med, Div Hematooncol, Cheonan, South Korea
[6] Yonsei Univ, Div Med Oncol, Dept Internal Med, Yonsei Canc Ctr, Seoul, South Korea
[7] Yonsei Univ, Med Oncol Dept, Yonsei Canc Ctr, Seoul, South Korea
[8] Seoul Natl Univ, Internal Med Dept, Bundang Hosp, Seongnam, South Korea
[9] Korea Univ, Guro Hosp, Dept Internal Med, Div Med Oncol, Seoul, South Korea
[10] Catholic Univ Korea, Internal Med Dept, Seoul, South Korea
[11] Seoul St Marys Hosp, Catholic Med Ctr, Seoul, South Korea
[12] Catholic Univ Korea, Seoul St Marys Hosp, Endocrinol, Seoul, South Korea
[13] Samsung Med Ctr SMC, Hematol & Med Oncol, Seoul, South Korea
[14] Ewha Womans Univ, Mokdong Hosp, Dept Internal Med, Div Hematol Oncol, Seoul, South Korea
[15] Natl Canc Ctr, Ctr Lung Canc, Goyang, South Korea
[16] Yonsei Univ, Coll Med, Dept Internal Med, Div Med Oncol, Seoul, South Korea
[17] Catholic Univ Korea, Dept Hosp Pathol, Yeouido St Marys Hosp, Coll Med, Seoul, South Korea
[18] Catholic Univ Korea, Dept Hosp Pathol, Seoul St Marys Hosp, Coll Med, Seoul, South Korea
[19] Catholic Univ Korea, Seoul St Marys Hosp, Catholic Med Ctr, Med Oncol Dept, Seoul, South Korea
关键词
D O I
10.1016/j.annonc.2024.10.517
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
492P
引用
收藏
页数:2
相关论文
共 50 条
  • [41] EFFICACY AND SAFETY OF LAROTRECTINIB IN PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS: AN EXPANDED DATASET
    Perreault, Sebastien
    Doz, Francois
    Drilon, Alexander
    Geoerger, Birgit
    Boni, Valentina
    Chisholm, Julia
    Dubois, Steven G.
    Grilley-Olson, Juneko E.
    Hong, David S.
    Italiano, Antoine
    Kang, HyoungJin
    Nysom, Karsten
    Ora, Ingrid
    Owens, Cormac
    Schulte, Johannes H.
    Tahara, Makoto
    Ziegler, David
    Ellezam, Benjamin
    Reeves, John A.
    Fellous, Marc
    De La Cuesta, Esther
    Laetsch, Theodore W.
    van Tilburg, Cornelis M.
    NEURO-ONCOLOGY, 2020, 22 : 58 - 58
  • [42] Updated efficacy and safety of larotrectinib in patients with tropomyosin receptor kinase (TRK) fusion lung cancer.
    Drilon, Alexander E.
    Lin, Jessica Jiyeong
    Kummar, Shivaani
    Tan, Daniel Shao-Weng
    Patel, Jyoti D.
    Lassen, Ulrik Niels
    Leyvraz, Serge
    Moreno, Victor
    Rosen, Lee S.
    Solomon, Benjamin Maurice
    Yachnin, Jeffrey
    Liu, Yongmei
    Dai, Ming-Shen
    Norenberg, Ricarda
    Fellous, Marc Mardoche
    Mussi, Chiara Erminia
    Shen, Lin
    JOURNAL OF CLINICAL ONCOLOGY, 2022, 40 (16)
  • [43] Efficacy and safety of larotrectinib in a pooled analysis of patients (Pts) with tropomyosin receptor kinase (TRK) fusion cancer
    Drilon, A.
    Shen, L.
    van Tilburg, C.
    Doz, F.
    Tan, D. S. W.
    Lin, J. J.
    Kummar, S.
    Lassen, U. N.
    McDermott, R. S.
    Dierselhuis, M. P.
    Albert, C. M.
    Nagasubramanian, R.
    Watt, T.
    Patil, T.
    Burcoveanu, D-I.
    Norenberg, R.
    Brega, N.
    Laetsch, T. W.
    Xu, R-H.
    Hong, D. S.
    ANNALS OF ONCOLOGY, 2023, 34 : S470 - S470
  • [44] Osimertinib and Selpercatinib Efficacy, Safety, and Resistance in a Multicenter, Prospectively Treated Cohort of EGFR-Mutant and RET Fusion-Positive Lung Cancers
    Rotow, Julia
    Patel, Jyoti D.
    Hanley, Matthew P.
    Yu, Helena
    Awad, Mark
    Goldman, Jonathan W.
    Nechushtan, Hovav
    Schef, Matthias
    Kuo, Chih-Hsi S.
    Rajappa, Senthil
    Harada, Guilherme
    Clifford, Sarah
    Santucci, Alison
    Silva, Laura
    Tupper, Rebecca
    Oxnard, Geoffrey R.
    Kherani, Jennifer
    Drilon, Alexander
    CLINICAL CANCER RESEARCH, 2023, 29 (16) : 2979 - 2987
  • [45] Improving Outcomes in Pediatric NTRK Gene Fusion-Positive Solid Tumors: Importance of Genomic Testing and Targeted Therapy With the TRK Inhibitor Larotrectinib
    Laetsch, Theodore W.
    CLINICAL ADVANCES IN HEMATOLOGY & ONCOLOGY, 2024, 22 (04)
  • [46] Entrectinib: A New Selective Tyrosine Kinase Inhibitor Approved for the Treatment of Pediatric and Adult Patients with NTRK Fusion-positive, Recurrent or Advanced Solid Tumors
    Osman, Hind M.
    Tuncbilek, Meral
    CURRENT MEDICINAL CHEMISTRY, 2022, 29 (15) : 2602 - 2616
  • [47] LONG-TERM EFFICACY AND SAFETY OF LAROTRECTINIB IN PATIENTS WITH TROPOMYOSIN RECEPTOR KINASE (TRK) FUSION PRIMARY CENTRAL NERVOUS SYSTEM (CNS) TUMORS
    Perreault, Sebastien
    Drilon, Alexander
    Lassen, Ulrik N.
    Geoerger, Birgit
    Nysom, Karsten
    Ora, Ingrid
    Gavrilovic, Igor T.
    Norenberg, Ricarda
    Bernard-Gauthier, Vadim
    De la Cuesta, Esther
    Laetsch, Theodore W.
    Doz, Francois
    Van Tilburg, Cornelis M.
    NEURO-ONCOLOGY, 2022, 24 : 87 - 87
  • [48] Updated Integrated Analysis of the Efficacy and Safety of Entrectinib in Patients with NTRK Fusion-Positive Solid Tumors (vol 28, pg 1302, 2022)
    Demetri, George D.
    De Braud, Filippo
    Drilon, Alexander
    Siena, Salvatore
    Patel, Manish R.
    Cho, Byoung Chul
    Liu, Stephen, V
    Ahn, Myung-Ju
    Chiu, Chao-Hua
    Lin, Jessica J.
    Goto, Koichi
    Lee, Jeeyun
    Bazhenova, Lyudmila
    John, Thomas
    Fakih, Marwan
    Chawla, Sant P.
    Dziadziuszko, Rafal
    Seto, Takashi
    Heinzmann, Sebastian
    Pitcher, Bethany
    Chen, David
    Wilson, Timothy R.
    Rolfo, Christian
    CLINICAL CANCER RESEARCH, 2022, 28 (10) : 2196 - 2196
  • [49] Long-term efficacy and safety of larotrectinib in patients with tropomyosin receptor kinase (TRK) fusion lung cancer
    Lin, Jessica Jiyeong
    Tan, Daniel Shao-Weng
    Kummar, Shivaani
    Patel, Jyoti D.
    Cermignani, Luciano
    Dai, Ming-Shen
    Lassen, Ulrik Niels
    Leyvraz, Serge
    Liu, Yongmei
    Moreno, Victor
    Rosen, Lee S.
    Saada-Bouzid, Esma
    Solomon, Benjamin Maurice
    Xu, Rui-Hua
    Yachnin, Jeffrey
    Norenberg, Ricarda
    Burcoveanu, Domnita-Ileana
    Mussi, Chiara E.
    Shen, Lin
    Drilon, Alexander E.
    JOURNAL OF CLINICAL ONCOLOGY, 2023, 41 (16)
  • [50] Long-term efficacy and safety of larotrectinib in patients with tropomyosin receptor kinase (TRK) fusion lung cancer
    Rieke, D. T.
    Lin, Iyeong J.
    Tan, D. S.
    Kummar, S.
    Patel, J. D.
    Cermignani, L.
    Dai, M. -S.
    Lassen, U. N.
    Leyvraz, S.
    Liu, Y.
    Moreno, V.
    Rosen, L.
    Saada-Bouzid, E.
    Solomon, B.
    Xu, R. -H.
    Yachnin, J.
    Norenberg, R.
    Burcoveanu, D. -I.
    Mussi, C. E.
    Shen, L.
    Drilon, A.
    ONCOLOGY RESEARCH AND TREATMENT, 2023, 46 : 9 - 10