The Role of SWI/SNF Complex in Bladder Cancer

被引：0
|
作者：
Lei, Zixiao [1 ,2 ]
Han, Yanfeng [1 ,2 ]
Liao, Jiejun [1 ,2 ]
Li, Xiaohong [1 ,2 ]
Su, Qisheng [1 ,2 ]
Yang, Zheng [1 ,2 ]
机构：
[1] Guangxi Med Univ, Affiliated Hosp 1, Dept Clin Lab, Nanning, Guangxi Zhuang, Peoples R China
[2] Guangxi Dept Educ, Key Lab Clin Lab Med, Nanning, Guangxi Zhuang, Peoples R China
来源：
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE | 2025年 / 29卷 / 01期
关键词：
bladder cancer; personalised treatment; SWI/SNF complex; DOUBLE-STRAND BREAKS; BACILLUS-CALMETTE-GUERIN; UROTHELIAL CARCINOMA; LUNG-CANCER; CELL CARCINOMA; ARID1A LOSS; PROMOTES; REPAIR; CHEMORESISTANCE; VULNERABILITY;
D O I：
10.1111/jcmm.70348
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Bladder cancer originates from bladder tissues and is the ninth most common type of cancer worldwide. The SWI/SNF (SWItch/sucrose non- fermentable) complex plays a crucial role in regulating various biological processes, such as cell cycle control, DNA damage repair and transcription regulation. The purpose of this article is to examine the functional studies of the SWI/SNF complex in bladder cancer, highlighting new pathways for creating personalised treatment approaches for bladder cancer patients with mutations in the SWI/SNF complex. By acquiring a comprehensive understanding of the mechanisms of the SWI/SNF complex in bladder cancer, we can offer more precise and effective solutions to treat this disease.
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页数：20
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