Additive manufacturing to fight cancer: Current Applications and Future Directions

被引：0

作者：

Duggal, Ishaan ^{[1
]}

Kim, Joon ^{[1
]}

Zhang, Yu ^{[1
,2
]}

Wang, Jiawei ^{[1
]}

Lu, Anqi ^{[1
]}

Maniruzzaman, Mohammed ^{[1
,2
]}

机构：

[1] Univ Texas Austin, Pharmaceut Engn & 3D Printing PharmE3D Lab, Coll Pharm, 2409 Univ Ave,A1920, Austin, TX 78712 USA

[2] Univ Mississippi, Sch Pharm, Dept Pharmaceut & Drug Delivery, PharmE3D Lab, Oxford, MS 38677 USA

来源：

DRUG DISCOVERY TODAY | 2024年 / 29卷 / 12期

关键词：

additive manufacturing; cancer; drug delivery; diagnostics; cancer models; microrobots; LONG-TERM EXPANSION; CELL-LINE; SCAFFOLDS; DELIVERY; SYSTEM; GROWTH; TUMORS; COLON; SKIN; NANOPARTICLES;

D O I：

10.1016/j.drudis.2024.104218

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

3D printing has emerged as a powerful tool demonstrating effectiveness in early screening and targeted delivery for various types of tumors. Although the applications of additive manufacturing for cancer are widespread, the issues of scaling up, quality control and specificity remain. This review presents a comprehensive analysis of the current landscape of use of additive manufacturing in cancer diagnostics and treatment. Furthermore, it proceeds to elucidate the prominent current and future applications of 4D- and 5D-printed micro-swimmers in cancer treatment with particular emphasis on the significant progress made in magnetic, biological and light-based propulsion microrobots. Lastly, the current limitations and future research directions are enumerated. In summary, this paper serves as a comprehensive exploration of the remarkable contributions of additive manufacturing to the diagnosis and treatment of cancer.

引用

页数：15

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