Treatment of Crohn's Disease With Infliximab and Subsequent Development of Takayasu's Arteritis

被引：0

作者：

Nomura, Kei ^{[1
]}

Shibuya, Tomoyoshi ^{[1
,2
]}

Furusho, Momoko ^{[1
]}

Ishino, Hirotaka ^{[1
]}

Orikasa, Masayuki ^{[1
]}

Omori, Masashi ^{[1
]}

Odakura, Rina ^{[1
]}

Koma, Masao ^{[1
]}

Ito, Kentaro ^{[1
]}

Maruyama, Takafumi ^{[1
]}

Ishikawa, Dai ^{[1
,2
]}

Hojo, Mariko ^{[1
,2
]}

Nagahara, Akihito ^{[1
,2
]}

机构：

[1] Juntendo Univ, Sch Med, Dept Gastroenterol, Bunkyo Ku, Tokyo 1138421, Japan

[2] Juntendo Univ, Sch Med, Dept Pathophysiol Res & Therapeut Gastrointestinal, Bunkyo Ku, Tokyo 1138421, Japan

来源：

GASTROENTEROLOGY RESEARCH | 2024年 / 17卷 / 5-6期

关键词：

Crohn's disease; Infliximab; Prednisolone; Takayasu's arteritis; INFLAMMATORY-BOWEL-DISEASE; ASSOCIATION; AORTITIS; PATIENT; CLASSIFICATION; MECHANISMS; VASCULITIS; CRITERIA;

D O I：

10.14740/gr1792

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

A 23-year-old man was diagnosed with Crohn's disease (CD) of the large intestine after colonoscopy revealed longitudinal ulcers, and pathology revealed non-caseating epithelioid cell granulomas and anal fistulas. The CD relapsed, and therefore prednisolone (PSL) and infliximab (IFX) treatment was initiated. The PSL was gradually tapered. Steroid-free remission was maintained with IFX. The patient subsequently developed a high fever and headache, while CD-related symptoms did not worsen. Laboratory data showed white blood cells at 14,200/mu L and C-reactive protein at 17.2 mg/ dL. Contrast-enhanced computed tomography revealed thoracoabdominal aortitis, and the patient was consequently diagnosed with ment that immediately reduced the fever and headache. The PSL to maintain CD remission. No further episodes of aortitis relapse were noted after restarting IFX, and the CD currently remains in investigate the possibility of vasculitis.

引用

页码：217 / 223

页数：7

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