Post-stroke fatigue interventions for stroke survivors: A scoping review

Background: Fatigue following a stroke, known as post-stroke fatigue (PSF), is a frequent complication experienced by individuals recovering from a stroke, with its incidence steadily increasing over time. The long-term presence of PSF significantly hinders the rehabilitation process and quality of life for these individuals. However, the most effective intervention strategies for PSF remain unclear. Therefore, it is crucial to implement appropriate intervention strategies at an early stage to prevent and manage PSF, thereby mitigating its negative impacts and promoting recovery in stroke survivors. Objective: This scoping review aimed to explore and chart the interventions available for managing post-stroke fatigue in individuals recovering from stroke, providing healthcare professionals with evidence to guide the development of optimal treatments. Design: A scoping review. Data Sources: This review conducted a systematic search across six databases-PubMed, Web of Science, Cochrane Library, Scopus and CINAHL (via EBSCO), and CNKI, for articles published from 10 January 2012 to early May 2024. Review Methods: This review followed the PRISMA-ScR reporting guidelines. Studies were selected based on the PCC framework, focusing on specific participants, concepts, and contexts. Exclusion criteria included ongoing studies without results, articles without full text, posters, reviews, and protocols. Tables and narrative descriptions were used to present relevant information on the interventions and their outcomes during the review process. Results: Twenty-seven studies were included, categorizing interventions for post-stroke fatigue into ten types: pharmacological treatments, physical activity, physical therapy, reduction, health education management, Traditional Chinese Medicine, and environmental enrichment. Conclusion: The interventions for post-stroke fatigue have demonstrated positive effects in alleviating fatigue symptoms among stroke survivors. However, some approaches have limitations, and the most effective treatment strategy remains unclear. The multidisciplinary collaboration between nurses and healthcare professionals plays a critical role in managing post-stroke fatigue by providing patients with education on fatigue prevention and treatment, along with personalized care plans, including one-on-one or group interventions. Future research should focus on increasing sample sizes and conducting multicenter trials to identify the most effective intervention strategies for managing post-stroke fatigue.