Structure-Based Virtual Screening for Novel Inhibitors of 3-oxoacyl-ACP Reductase in Plasmodium Falciparum

被引:0
|
作者
Patil, Arnav [1 ]
Beckham, Josh T. [1 ]
机构
[1] Univ Texas Austin, Austin, TX 78712 USA
关键词
D O I
暂无
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
W64
引用
收藏
页码:198 / 198
页数:1
相关论文
共 50 条
  • [41] Design, Synthesis, and Biological and Crystallographic Evaluation of Novel Inhibitors of Plasmodium falciparum Enoyl-ACP-reductase (PfFabl)
    Belluti, Federica
    Perozzo, Remo
    Lauciello, Leonardo
    Colizzi, Francesco
    Kostrewa, Dirk
    Bisi, Alessandra
    Gobbi, Silvia
    Rampa, Angela
    Bolognesi, Maria Laura
    Recanatini, Maurizio
    Brun, Reto
    Scapozza, Leonardo
    Cavalli, Andrea
    JOURNAL OF MEDICINAL CHEMISTRY, 2013, 56 (19) : 7516 - 7526
  • [42] In-silico Identification of Triclosan Analogs as Novel Inhibitors of Enoyl-ACP Reductase from Plasmodium falciparum
    Singh, Pushpendra
    Srivastava, Vivek
    BIOSCIENCE BIOTECHNOLOGY RESEARCH COMMUNICATIONS, 2021, 14 (02): : 836 - 841
  • [43] Structure-based pharmacophore modeling, virtual screening, and molecular dynamics simulation studies for identification of Plasmodium falciparum 5-aminolevulinate synthase inhibitors
    Oduselu, Gbolahan O.
    Afolabi, Rufus
    Ademuwagun, Ibitayo
    Vaughan, Ashley
    Adebiyi, Ezekiel
    FRONTIERS IN MEDICINE, 2023, 9
  • [44] Identification of novel inhibitors of glucose transporter 3 (GLUT3) through structure-based virtual screening
    Zhang, Sixue
    Libby, Catherin
    Augelli-Szafran, Corinne
    Hjelmeland, Anita
    Zhang, Wei
    ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY, 2017, 254
  • [45] Structure-based design of inhibitors of key proteins in Trypanosoma brucei and Plasmodium falciparum
    Verlinde, C
    Bernstein, B
    Kim, HD
    Chudzik, D
    Baca, A
    Wooden, J
    Li, RB
    Choe, JW
    Bressi, J
    Gelb, M
    Blackburn, M
    Fan, E
    Hol, WGJ
    NAUNYN-SCHMIEDEBERGS ARCHIVES OF PHARMACOLOGY, 1998, 358 (01) : R27 - R27
  • [46] Structure-activity relationship of novel DAPK inhibitors identified by structure-based virtual screening
    Okamoto, Masako
    Takayama, Kiyoshi
    Shimizu, Tomoko
    Muroya, Ayumu
    Furuya, Toshio
    BIOORGANIC & MEDICINAL CHEMISTRY, 2010, 18 (07) : 2728 - 2734
  • [47] Discovery of new potential hits of Plasmodium falciparum enoyl-ACP reductase through ligand- and structure-based drug design approaches
    Neves, Bruno J.
    Bueno, Renata V.
    Braga, Rodolpho C.
    Andrade, Carolina H.
    BIOORGANIC & MEDICINAL CHEMISTRY LETTERS, 2013, 23 (08) : 2436 - 2441
  • [48] Structure-based drug discovery for Plasmodium falciparum
    Mehlin, C
    COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING, 2005, 8 (01) : 5 - 14
  • [49] Ligand-based 3D-QSAR analysis and virtual screening in exploration of new scaffolds as Plasmodium falciparum glutathione reductase inhibitors
    P. Kamaria
    N. Kawathekar
    Medicinal Chemistry Research, 2014, 23 : 25 - 33
  • [50] Discovery of Novel HPK1 Inhibitors Through Structure-Based Virtual Screening
    Ge, Huizhen
    Peng, Lizeng
    Sun, Zhou
    Liu, Huanxiang
    Shen, Yulin
    Yao, Xiaojun
    FRONTIERS IN PHARMACOLOGY, 2022, 13