Investigating the Impact of the Number of Medication Use on Depression Among Hypertensive Patients: Results from the National Health and Nutrition Examination Survey Database

被引:0
|
作者
Alsulami, Fahad T. [1 ]
Almalki, Atiah H. [2 ,3 ]
Algarni, Majed A. [1 ]
Alzahrani, Mohammad S. [1 ]
Alqarni, Yousef Saeed [4 ]
机构
[1] Taif Univ, Coll Pharm, Dept Clin Pharm, POB 11099, Taif 21944, Saudi Arabia
[2] Taif Univ, Coll Pharm, Dept Pharmaceut Chem, POB 11099, Taif 21944, Saudi Arabia
[3] Taif Univ, Addict & Neurosci Res Unit, Hlth Sci Campus,POB 11099, Taif 21944, Saudi Arabia
[4] Imam Abdulrahman Bin Faisal Univ, Coll Clin Pharm, Dept Pharm Practice, POB 1982, Dammam 31441, Saudi Arabia
来源
MEDICINA-LITHUANIA | 2024年 / 60卷 / 10期
关键词
polypharmacy; hypertension; depression; cardiovascular diseases; mental health; POLYPHARMACY; PHQ-9;
D O I
10.3390/medicina60101708
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Background and Objective: Hypertension is a prevalent chronic condition often treated with multiple medications, leading to polypharmacy, which can heighten the risk of adverse drug reactions and contribute to psychological issues like depression. This study aimed to investigate the relationship between polypharmacy and depressive symptoms in hypertensive patients using data from the National Health and Nutrition Examination Survey (NHANES) from 2017 to 2020. Materials and Methods: This study utilized data from the National Health and Nutrition Examination Survey (NHANES) collected between 2017 and March 2020. Results: Among 2543 hypertensive participants, 12.3% met the criteria for depression. The findings revealed that patients using 11 or more medications were ten times more likely to experience depressive symptoms compared to those taking 1 to 2 medications (OR = 10.06, p < 0.001). Additionally, younger age (18 to 45 years), female gender, and lower educational attainment were significantly associated with higher rates of depressive symptoms. Specifically, females were 1.47 times more likely to experience depression compared to males (p = 0.032). Conclusions: This research highlights the substantial impact of medication burden on mental health among hypertensive patients, emphasizing the need for tailored clinical interventions for this vulnerable population.
引用
收藏
页数:13
相关论文
共 50 条
  • [21] Association of oral health behaviors and status with depression: results from the Korean National Health and Nutrition Examination Survey, 2010
    Park, Se Jin
    Ko, Ki Dong
    Shin, Seung-Il
    Ha, Yu Jeong
    Kim, Gy Young
    Kim, Hyoung Ah
    JOURNAL OF PUBLIC HEALTH DENTISTRY, 2014, 74 (02) : 127 - 138
  • [22] Iron supplement use and iron status among US adults: results from the third National Health and Nutrition Examination Survey
    Blanck, HM
    Cogswell, ME
    Gillespie, C
    Reyes, M
    AMERICAN JOURNAL OF CLINICAL NUTRITION, 2005, 82 (05): : 1024 - 1031
  • [23] A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey
    Patel, Chirag J.
    Pho, Nam
    McDuffie, Michael
    Easton-Marks, Jeremy
    Kothari, Cartik
    Kohane, Isaac S.
    Avillach, Paul
    SCIENTIFIC DATA, 2016, 3
  • [24] A database of human exposomes and phenomes from the US National Health and Nutrition Examination Survey
    Chirag J. Patel
    Nam Pho
    Michael McDuffie
    Jeremy Easton-Marks
    Cartik Kothari
    Isaac S. Kohane
    Paul Avillach
    Scientific Data, 3
  • [25] Adolescent nutritional awareness and use of food labels: Results from the national nutrition health and examination survey
    Wojcicki, Janet M.
    Heyman, Melvin B.
    BMC PEDIATRICS, 2012, 12
  • [26] Adolescent nutritional awareness and use of food labels: Results from the national nutrition health and examination survey
    Janet M Wojcicki
    Melvin B Heyman
    BMC Pediatrics, 12
  • [27] Urinary incontinence prevalence: Results from the National Health and Nutrition Examination Survey
    Dooley, Yashika
    Kenton, Kimberly
    Cao, Guichan
    Luke, Amy
    Durazo-Arvizu, Ramon
    Kramer, Holly
    Brubaker, Linda
    JOURNAL OF UROLOGY, 2008, 179 (02): : 656 - 661
  • [28] Comorbidities of Gout: Results from the Korean National Health and Nutrition Examination Survey
    Jeong, Hyemin
    Jeon, Chan Hong
    ARTHRITIS & RHEUMATOLOGY, 2023, 75 : 485 - 485
  • [29] Gout comorbidities: results from the Korean National Health and Nutrition Examination Survey
    Jeong, Hyemin
    Chang, Young-Soo
    Jeon, Chan Hong
    ADVANCES IN RHEUMATOLOGY, 2024, 64 (01):
  • [30] Medication use and obesity in Brazil: results from the National Health Survey
    Rimes-Dias, Karina Abibi
    Canella, Daniela Silva
    SCIENTIFIC REPORTS, 2020, 10 (01)