Targeting an Fgfr3 Enhancer as a Potential Therapeutic Tool for Achondroplasia

被引：0
|
作者：
Angelozzi, Marco [1 ]
Molin, Arnaud [1 ]
Karvande, Anirudha [1 ]
Fernandez-Iglesias, Angela [1 ]
Haseeb, Abdul [1 ]
Whipple, Samantha [1 ]
Lefebvre, Veronique [1 ]
机构：
[1] Childrens Hosp Philadelphia, Philadelphia, PA USA
来源：
JOURNAL OF BONE AND MINERAL RESEARCH | 2024年 / 39卷
关键词：
D O I：
暂无
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
FRI-159
引用
收藏
页码：28 / 29
页数：2
相关论文
共 50 条
  • [41] Acanthosis Nigricans and Insulin Sensitivity in Patients with Achondroplasia and Hypochodroplasia due to FGFR3 Mutations
    Alatzoglou, Kyriaki S.
    Hindmarsh, Peter C.
    Brain, Caroline
    Torpiano, John
    Dattani, Mehul T.
    JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2009, 94 (10): : 3959 - 3963
  • [42] Early postnatal soluble FGFR3 therapy prevents the atypical development of obesity in achondroplasia
    Saint-Laurent, Celine
    Garcia, Stephanie
    Sarrazy, Vincent
    Dumas, Karine
    Authier, Florence
    Sorel, Sophie
    Tran, Albert
    Gual, Philippe
    Gennero, Isabelle
    Salles, Jean-Pierre
    Gouze, Elvire
    PLOS ONE, 2018, 13 (04):
  • [43] Targetable FGFR3 Fusions and Novel FGFR3 Mutations in Glioma
    Schittenhelm, Jens
    Ziegler, Lukas
    Mittelbronn, Michel
    Capper, David
    Burghardt, Isabel
    Poso, Antti
    Biskup, Saskia
    Skardelly, Marko
    Tabatabal, Ghazaleh
    ONCOLOGY RESEARCH AND TREATMENT, 2020, 43 : 33 - 33
  • [44] Knock-in human FGFR3 achondroplasia mutation as a mouse model for human skeletal dysplasia
    Yi-Ching Lee
    I-Wen Song
    Ya-Ju Pai
    Sheng-De Chen
    Yuan-Tsong Chen
    Scientific Reports, 7
  • [45] FGFR3 is key
    Gemma K. Alderton
    Nature Reviews Cancer, 2009, 9 : 387 - 387
  • [46] FGFR3 as a therapeutic target in squamous cell lung carcinoma
    Liao, Rachel
    Hammerman, Peter
    Sivachenko, Andrey
    Greulich, Heidi
    Getz, Gad
    Liu, Qingsong
    Gray, Nathanael
    Meyerson, Matthew
    CANCER RESEARCH, 2012, 72
  • [47] Postnatal Soluble FGFR3 Therapy Rescues Achondroplasia Symptoms and Restores Bone Growth in Mice
    Garcia, Stephanie
    Dirat, Beatrice
    Tognacci, Thomas
    Rochet, Nathalie
    Mouska, Xavier
    Bonnafous, Stephanie
    Patouraux, Stephanie
    Albert Tran
    Gual, Philippe
    Le Marchand-Brustel, Yannick
    Gennero, Isabelle
    Gouze, Elvire
    SCIENCE TRANSLATIONAL MEDICINE, 2013, 5 (203)
  • [48] A novel mutation Ser344Cys in FGFR3 causes achondroplasia with severe platyspondyly
    Takagi, Masaki
    Kouwaki, Masanori
    Kawase, Koya
    Shinohara, Hiroyuki
    Hasegawa, Yukihiro
    Yamada, Takahiro
    Fujiwara, Ikuma
    Sawai, Hideaki
    Nishimura, Gen
    Hasegawa, Tomonobu
    AMERICAN JOURNAL OF MEDICAL GENETICS PART A, 2015, 167 (11) : 2851 - 2854
  • [49] Meclozine Facilitates Proliferation and Differentiation of Chondrocytes by Attenuating Abnormally Activated FGFR3 Signaling in Achondroplasia
    Matsushita, Masaki
    Kitoh, Hiroshi
    Ohkawara, Bisei
    Mishima, Kenichi
    Kaneko, Hiroshi
    Ito, Mikako
    Masuda, Akio
    Ishiguro, Naoki
    Ohno, Kinji
    PLOS ONE, 2013, 8 (12):
  • [50] Achondroplasia in Turkey is defined by recurrent G380R mutation of the FGFR3 gene
    Pehlivan, S
    Özkinay, F
    Okutman, Ö
    Çogulu, Ö
    Özcan, A
    Çankaya, T
    Ülgenalp, A
    TURKISH JOURNAL OF PEDIATRICS, 2003, 45 (02) : 99 - 101
12345