Targeting an Fgfr3 Enhancer as a Potential Therapeutic Tool for Achondroplasia

被引:0
|
作者
Angelozzi, Marco [1 ]
Molin, Arnaud [1 ]
Karvande, Anirudha [1 ]
Fernandez-Iglesias, Angela [1 ]
Haseeb, Abdul [1 ]
Whipple, Samantha [1 ]
Lefebvre, Veronique [1 ]
机构
[1] Childrens Hosp Philadelphia, Philadelphia, PA USA
关键词
D O I
暂无
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
FRI-159
引用
收藏
页码:28 / 29
页数:2
相关论文
共 50 条
  • [1] FGFR3 targeting strategies for achondroplasia
    Laederich, Melanie B.
    Horton, William A.
    EXPERT REVIEWS IN MOLECULAR MEDICINE, 2012, 14
  • [2] Fate of FGFR3 in achondroplasia
    Horton, William A.
    Lunstrum, Gregory P.
    Degnin, Catherine R.
    Laederich, Melanie B.
    ENDOCRINE JOURNAL, 2010, 57 : S247 - S247
  • [3] Evaluation of the Therapeutic Potential of a CNP Analog in a Fgfr3 Mouse Model Recapitulating Achondroplasia
    Lorget, Florence
    Kaci, Nabil
    Peng, Jeff
    Benoist-Lasselin, Catherine
    Mugniery, Emilie
    Oppeneer, Todd
    Wendt, Dan J.
    Bell, Sean M.
    Bullens, Sherry
    Bunting, Stuart
    Tsuruda, Laurie S.
    O'Neill, Charles A.
    Di Rocco, Federico
    Munnich, Arnold
    Legeai-Mallet, Laurence
    AMERICAN JOURNAL OF HUMAN GENETICS, 2012, 91 (06) : 1108 - 1114
  • [4] Development of Recifercept, a FGFR3 decoy protein, as a potential treatment for Achondroplasia
    Czech, Christian
    Slade, Alison
    Goncalves, Diogo
    Roberts, Kevin
    Dawra, Vikas Kumar
    Rignol, Guylene
    JOURNAL OF BONE AND MINERAL RESEARCH, 2023, 38 : 170 - 170
  • [5] Quantification of lateral associations of achondroplasia in FGFR3
    McKenzie, Daniel M.
    Hristova, Kalina
    Roy, Tanaya
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 196A - 196A
  • [6] Fgfr3 enhancer deletion markedly improves all skeletal features in a mouse model of achondroplasia
    Angelozzi, Marco
    Molin, Arnaud
    Karvande, Anirudha
    Fernandez-Iglesias, Angela
    Whipple, Samantha
    Bloh, Andrew M.
    Lefebvre, Veronique
    JOURNAL OF CLINICAL INVESTIGATION, 2025, 135 (02):
  • [7] Number and brightness studies of the FGFR3 achondroplasia mutant
    Roy, Tanaya
    Hristova, Kalina
    BIOPHYSICAL JOURNAL, 2023, 122 (03) : 56A - 56A
  • [8] Bone: FGFR3 mutation delays bone age in achondroplasia
    Koch L.
    Nature Reviews Endocrinology, 2010, 6 (11) : 596 - 596
  • [9] Achondroplasia phenotype due to novel FGFR3 mutation.
    Zabel, BU
    Hilbert, K
    Beck, M
    Stelzer, C
    Wildhardt, G
    Winterpacht, A
    Spranger, J
    AMERICAN JOURNAL OF HUMAN GENETICS, 2000, 67 (04) : 388 - 388
  • [10] FGFR3 mutation causes abnormal membranous ossification in achondroplasia
    Di Rocco, Federico
    Duplan, Martin Biosse
    Heuze, Yann
    Kaci, Nabil
    Komla-Ebri, Davide
    Munnich, Arnold
    Mugniery, Emilie
    Benoist-Lasselin, Catherine
    Legeai-Mallet, Laurence
    HUMAN MOLECULAR GENETICS, 2014, 23 (11) : 2914 - 2925