Preparation and evaluation of polymeric ionic liquid functionalized microparticles as the efficient adsorbent for pipette tip solid phase extraction of sulfonamides

Sulfonamides (SAs) residues are commonly found in environmental samples, which is highly concerning for public safety and environmental protection. The detection of SAs is quite important but challenging. In this work, a kind of polymeric ionic liquid functionalized microparticles (PIL-FM) was synthesized via a simple free radical polymerization reaction, and applied as the adsorbent for pipette tip solid phase extraction (PT-SPE) of three SAs from river water, milk powder and honey samples. The adsorption performance of PIL-FM on SAs were evaluated using adsorption kinetics and adsorption isotherms, and the results showed that PIL-FM had the best selectivity for SMZ with the maximum adsorption capacity was as high as 45.05 mg center dot g(- 1.) The extraction process was optimized and the adsorption mechanism was preliminarily discussed. PIL-FM has the excellent selectivity for SAs mainly because of the strong it-it interaction, and the electrostatic repulsion between them in the elution step also has a positive impact. Under optimal conditions, combined with HPLC, this PT-SPE method had wide linearity (0.2-100 mu g center dot L-1, R-2 > 0.9998) and low limits of detection (0.06-0.08 mu g center dot L-1). The intra-day and interday repeatability were found to be 3.7 %-4.6 % and 4.5 %-6.2 %, respectively. The suggested PT-SPE method is simple, low cost, rapid, and efficient to extract SAs, and can be applied for the monitoring of SAs residues in the aquatic environment and in food.