Optimization and Implication of Adipose-Derived Stem Cells in Craniofacial Bone Regeneration and Repair

被引:0
|
作者
Gu, Cong [1 ]
Tang, Qinghuang [1 ,2 ]
Li, Liwen [1 ,3 ]
Chen, Yiping [1 ]
机构
[1] Tulane Univ, Dept Cell & Mol Biol, New Orleans, LA 70118 USA
[2] SUNY Buffalo, Sch Dent Med, Dept Oral Biol, Buffalo, NY 14214 USA
[3] SUNY Buffalo, Dept Biol Sci, Buffalo, NY 14260 USA
来源
BIOENGINEERING-BASEL | 2024年 / 11卷 / 11期
关键词
adipose-derived stem cells; ADSCs; craniofacial bone regeneration;
D O I
10.3390/bioengineering11111100
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Adipose-derived stem cells (ADSCs) have emerged as a promising resource for craniofacial bone regeneration due to their high abundance and easy accessibility, significant osteogenic potential, versatile applications, and potential for personalized medicine, which underscore their importance in this field. This article reviews the current progress of preclinical studies that describe the careful selection of specific ADSC subpopulations, key signaling pathways involved, and usage of various strategies to enhance the osteogenic potential of ADSCs. Additionally, clinical case reports regarding the application of ADSCs in the repair of calvarial defects, cranio-maxillofacial defects, and alveolar bone defects are also discussed.
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页数:19
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