Regulation of the ATR-CHK1 checkpoint signaling

被引：0
|
作者：
Xu, Xingzhi [1 ]
机构：
[1] Shenzhen Univ, Sch Med, Shenzhen, Peoples R China
来源：
CANCER SCIENCE | 2025年 / 116卷
关键词：
D O I：
暂无
中图分类号：
R73 [肿瘤学];
学科分类号：
100214 ;
摘要：
IS08-6
引用
收藏
页码：824 / 824
页数：1
相关论文
共 50 条
  • [31] ATR-Chk1 axis is activated, but the function of Chk1 is disrupted in BCR/ABL leukemia cells responding to DNA damage
    Nieborowska, M
    Stoklosa, T
    Datta, M
    Czechowska, A
    Rink, L
    Blasiak, J
    Skorski, T
    BLOOD, 2005, 106 (11) : 808A - 808A
  • [32] Hyperoxia activates the ATR-Chk1 pathway and phosphorylates p53 at multiple sites
    Das, KC
    Dashnamoorthy, R
    AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY, 2004, 286 (01) : L87 - L97
  • [33] Insulin-like Growth Factor 1 Receptor Signaling Is Required for Optimal ATR-CHK1 Kinase Signaling in Ultraviolet B (UVB)-irradiated Human Keratinocytes
    Kemp, Michael G.
    Spandau, Dan F.
    Simman, Richard
    Travers, Jeffrey B.
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2017, 292 (04) : 1231 - 1239
  • [34] Interactions of Human Mismatch Repair Proteins MutSα and MutLα with Proteins of the ATR-Chk1 Pathway
    Liu, Yiyong
    Fang, Yanan
    Shao, Hongbing
    Lindsey-Boltz, Laura
    Sancar, Aziz
    Modrich, Paul
    JOURNAL OF BIOLOGICAL CHEMISTRY, 2010, 285 (08) : 5974 - 5982
  • [35] ACTL6A deficiency induces apoptosis through impairing DNA replication and inhibiting the ATR-Chk1 signaling in glioblastoma cells
    Hu, Xiaosong
    Pei, Dakun
    Ci, Mingxin
    Zhang, Guanghui
    Li, Benqin
    Wang, Jie
    Shen, Yue
    Zhai, Xuan
    Liang, Ping
    Cui, Hongjuan
    BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 2022, 599 : 148 - 155
  • [36] Interactions of human mismatch repair proteins MutSalpha and MutLalpha with proteins of the ATR-Chk1 pathway
    Liu, Yiyong
    Fang, Yanan
    Shao, Hongbing
    Lindsey-boltz, Laura
    Sancar, Aziz
    Modrich, Paul
    FASEB JOURNAL, 2010, 24
  • [37] Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer
    Guo, Yuchen
    Wang, Jun
    Benedict, Bente
    Yang, Chen
    van Gemert, Frank
    Ma, Xuhui
    Gao, Dongmei
    Wang, Hui
    Zhang, Shu
    Lieftink, Cor
    Beijersbergen, Roderick L.
    Te Riele, Hein
    Qiao, Xiaohang
    Gao, Qiang
    Sun, Chong
    Qin, Wenxin
    Bernards, Rene
    Wang, Cun
    GENOME MEDICINE, 2021, 13 (01)
  • [38] Inhibition of ATR-Chk1 signaling blocks DNA double-strand-break repair and induces cytoplasmic vacuolization in metastatic osteosarcoma
    Li, Xiaoyang
    Dean, Dylan C.
    Cote, Gregory M.
    Zou, Lee
    Hornicek, Francis J.
    Yu, Shengji
    Duan, Zhenfeng
    THERAPEUTIC ADVANCES IN MEDICAL ONCOLOGY, 2020, 12
  • [39] Targeting CDC7 potentiates ATR-CHK1 signaling inhibition through induction of DNA replication stress in liver cancer
    Yuchen Guo
    Jun Wang
    Bente Benedict
    Chen Yang
    Frank van Gemert
    Xuhui Ma
    Dongmei Gao
    Hui Wang
    Shu Zhang
    Cor Lieftink
    Roderick L. Beijersbergen
    Hein te Riele
    Xiaohang Qiao
    Qiang Gao
    Chong Sun
    Wenxin Qin
    René Bernards
    Cun Wang
    Genome Medicine, 13
  • [40] Targeting the ATR-Chk1 axis with PARP inhibition results in tumor regression in BRCA mutant models
    George, E.
    Kim, H.
    Ragland, R.
    Rafail, S.
    Zhang, R.
    Krepler, C.
    Morgan, M. A.
    Herlyn, M.
    Brown, E.
    Simpkins, F.
    GYNECOLOGIC ONCOLOGY, 2017, 145 : 100 - 100
12345