Impact of adipose-derived mesenchymal stem cells and their secretome on osteoarthritis in a rat model

被引:0
|
作者
Silvia Palombella [1 ]
Silvia Lopa [1 ]
Camilla Recordati [2 ]
Simone Canesi [3 ]
Matteo Moretti [2 ]
Arianna B. Lovati [3 ]
机构
[1] IRCCS Istituto Ortopedico Galeazzi,Cell and Tissue Engineering Laboratory
[2] University of Milan,Department of Veterinary Medicine and Animal Sciences
[3] UniMi Foundation,Mouse and Animal Pathology Laboratory (MAPLab)
[4] Ente Ospedaliero Cantonale,Regenerative Medicine Technologies Lab, Laboratories for Translational Research
[5] Ente Ospedaliero Cantonale,Service of Orthopaedics and Traumatology, Department of Surgery
[6] Università Della Svizzera Italiana (USI),Euler Institute, Biomedical Sciences Faculty
关键词
Adipose-derived mesenchymal stem cells; Secretome; Human platelet lysate; Osteoarthritis; Rat model; Immune response;
D O I
10.1186/s12891-025-08642-8
中图分类号
学科分类号
摘要
引用
收藏
相关论文
共 50 条
  • [21] Xenotransplant of human adipose-derived mesenchymal stem cells
    Meyerrose, T
    DeUgarte, DA
    McNamara, G
    Hedrick, MH
    Nolta, JA
    EXPERIMENTAL HEMATOLOGY, 2002, 30 (06) : 142 - 142
  • [22] Adipose-derived mesenchymal stem cells and regenerative medicine
    Konno, Masamitsu
    Hamabe, Atsushi
    Hasegawa, Shinichiro
    Ogawa, Hisataka
    Fukusumi, Takahito
    Nishikawa, Shimpei
    Ohta, Katsuya
    Kano, Yoshihiro
    Ozaki, Miyuki
    Noguchi, Yuko
    Sakai, Daisuke
    Kudoh, Toshihiro
    Kawamoto, Koichi
    Eguchi, Hidetoshi
    Satoh, Taroh
    Tanemura, Masahiro
    Nagano, Hiroaki
    Doki, Yuichiro
    Mori, Masaki
    Ishii, Hideshi
    DEVELOPMENT GROWTH & DIFFERENTIATION, 2013, 55 (03) : 309 - 318
  • [23] Secretome of human adipose-derived mesenchymal stem cell relieves pain and neuroinflammation independently of the route of administration in experimental osteoarthritis
    Amodeo, Giada
    Niada, Stefania
    Moschetti, Giorgia
    Franchi, Silvia
    Savadori, Paolo
    Brini, Anna T.
    Sacerdote, Paola
    BRAIN BEHAVIOR AND IMMUNITY, 2021, 94 : 29 - 40
  • [24] Impact of Antibiotics on the Proliferation and Differentiation of Human Adipose-Derived Mesenchymal Stem Cells
    Skubis, Aleksandra
    Gola, Joanna
    Sikora, Bartosz
    Hybiak, Jolanta
    Paul-Samojedny, Monika
    Mazurek, Urszula
    Los, Marek J.
    INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 2017, 18 (12)
  • [25] Combination of preconditioned adipose-derived mesenchymal stem cells and platelet-rich plasma improves the repair of osteoarthritis in rat
    Ahmad, Muhammad Rauf
    Badar, Wafa
    Khan, Muhammad Azmat Ulla
    Mahmood, Azra
    Latif, Noreen
    Iqbal, Tariq
    Assir, Muhammad Zaman Khan
    Sleem, Mushtaq A.
    REGENERATIVE MEDICINE, 2020, 15 (11) : 2285 - 2295
  • [26] Use of Adipose-Derived Mesenchymal Stem Cells in Keratoconjunctivitis Sicca in a Canine Model
    Villatoro, Antonio J.
    Fernandez, Viviana
    Claros, Silvia
    Rico-Llanos, Gustavo A.
    Becerra, Jose
    Andrades, Jose A.
    BIOMED RESEARCH INTERNATIONAL, 2015, 2015
  • [27] ADIPOSE-DERIVED STEM CELL SECRETOME TRIGGERS TGFß-PSMAD SIGNALING IN CHONDROCYTES AND IS A PROMISING THERAPY FOR OSTEOARTHRITIS MODEL
    Lu, H.
    Buddhakosai, W.
    Hsueh, Y.
    Le, P.
    Chen, W.
    Tu, Y.
    CYTOTHERAPY, 2023, 25 (06) : S117 - S117
  • [28] Myogenic Differentiation and Immunomodulatory Properties of Rat Adipose-Derived Mesenchymal Stem/Stromal Cells
    Ngeun, Sai Koung
    Shimizu, Miki
    Kaneda, Masahiro
    BIOLOGY-BASEL, 2024, 13 (02):
  • [29] Regulation of Osteogenesis by Wnt Signaling in Rat Mesenchymal and Human Adipose-Derived Stem Cells
    Regmi, A.
    Yang, X.
    Galvin, R. J.
    Geiser, A. G.
    JOURNAL OF BONE AND MINERAL RESEARCH, 2008, 23 : S253 - S253
  • [30] The impact of electroconductive multifunctional composite nanofibrous scaffold on adipose-derived mesenchymal stem cells
    Slysz, Anna
    Siennicka, Katarzyna
    Kijenska-Gawronska, Ewa
    Debski, Tomasz
    Zolocinska, Aleksandra
    Swieszkowski, Wojciech
    Pojda, Zygmunt
    TISSUE & CELL, 2022, 78