Efficacy and safety of mirikizumab as induction and maintenance treatment in adults 60 years or older with moderately to severely active ulcerative colitis

被引:0
|
作者
Sturm, A. [1 ]
Sebastian, S. [2 ]
Faye, A. S. [3 ]
Armuzzi, A. [4 ]
Buisson, A. [5 ]
Halfvarson, J. [6 ]
Zeissig, S. [7 ,8 ]
Kochar, B. [9 ]
Maier, S. [10 ]
Redondo, I [10 ]
Moses, R. E. [10 ]
Keohane, A. [11 ]
Watanabe, K. [12 ]
机构
[1] DRK Kliniken Berlin Westend, Dept Gastroenterol, Berlin, Germany
[2] Hull Univ Teaching Hosp, IBD Unit, Kingston Upon Hull, England
[3] NYU Langone Hlth, Inflammatory Bowel Dis Ctr, New York, NY USA
[4] IRCCS Humanitas Res Hosp, IBD Ctr, Milan, Italy
[5] Univ Clermont Auvergne, CHU Clermont Ferrand, Serv Hepatogastroenterol, Inserm,3iHP, Clermont Ferrand, France
[6] Orebro Univ, Dept Gastroenterol, Orebro, Sweden
[7] Univ Med Greifswald, Dept Internal Med A, Greifswald, Germany
[8] Tech Univ TU Dresden, Med Fac, Dresden, Germany
[9] Massachusetts Gen Hosp, Gastroenterol Unit, Boston, MA USA
[10] Eli Lilly & Co, Lilly Immunol, Indianapolis, IN USA
[11] HaaPACS GmbH, Stat Europe, Schriesheim, Germany
[12] Univ Toyama, Dept Internal Med Inflammatory Bowel Dis, Toyama, Japan
来源
关键词
D O I
10.1093/ecco-jcc/jjae190.1263
中图分类号
R57 [消化系及腹部疾病];
学科分类号
摘要
P1089
引用
收藏
页码:i2005 / i2006
页数:2
相关论文
共 50 条
  • [41] REDUCTION IN INFLAMMATORY BIOMARKERS IN A PHASE 2 STUDY OF MIRIKIZUMAB IN THE TREATMENT OF PATIENTS WITH MODERATELY-TO-SEVERELY ACTIVE ULCERATIVE COLITIS
    Sandborn, William J.
    Sands, Bruce E.
    Kobayashi, Taku
    Tuttle, Jay
    Schmitz, Jochen
    Durante, Michael
    Higgs, Richard E.
    Canavan, James
    Siegel, Robert
    Ferrante, Marc
    GASTROENTEROLOGY, 2019, 156 (06) : S1094 - S1095
  • [42] Adalimumab for Induction of Histological Remission in Moderately to Severely Active Ulcerative Colitis
    J. Ignacio Fernández-Blanco
    Guillermo Fernández-Díaz
    Carlos Cara
    María I. Vera
    David Olivares
    Carlos Taxonera
    Digestive Diseases and Sciences, 2018, 63 : 731 - 737
  • [43] EXTENDED TREATMENT WITH MIRIKIZUMAB IN PATIENTS WITH MODERATELY-TO-SEVERELY ACTIVE ULCERATIVE COLITIS: RESULTS FROM A PHASE 2 TRIAL
    Sandborn, William J.
    Ferrante, Marc
    Bhandari, Bal R.
    Berliba, Elina
    Hibi, Toshifumi
    D'Haens, Geert R.
    Tuttle, Jay
    Krueger, Kathryn A.
    Friedrich, Stuart
    Durante, Michael
    Arora, Vipin
    Feagan, Brian G.
    GASTROENTEROLOGY, 2019, 156 (06) : S1094 - S1094
  • [44] The efficacy and safety of adalimumab for patients with moderately to severely active ulcerative colitis and predictors of response in Korea
    Shin, S. Shin
    Park, S. J.
    Kim, Y.
    Im, J. P.
    Kim, H. J.
    Lee, K. M.
    Kim, J. W.
    Jung, S. A.
    Lee, J.
    Kang, S. B.
    Shin, S. J.
    Kim, E. S.
    Kim, Y. S.
    Kim, T. O.
    Kim, H. S.
    Park, D. I.
    Kim, H. K.
    Kim, E. S.
    Kim, Y. H.
    Kim, D. H.
    Teng, D.
    Kim, J. H.
    Kim, W. Y.
    Choi, C. H.
    JOURNAL OF CROHNS & COLITIS, 2020, 14 : S432 - S432
  • [45] Risankizumab Maintenance Therapy in Patients With Moderately to Severely Active Ulcerative Colitis: Efficacy and Safety in the Randomised Phase 3 COMMAND Study
    Louis, E.
    Panaccione, R.
    Parkes, G.
    Peyrin-Biroulet, L.
    Ferrante, M.
    Hisamatsu, T.
    Siegmund, B.
    Kalabic, J.
    Levine, P.
    Neimark, E.
    Wallace, K.
    Chen, S.
    Cheng, L.
    Duan, W. R.
    Armuzzi, A.
    Biederman, L.
    Loftus, E.
    Melmed, G.
    Schreiber, S.
    JOURNAL OF CROHNS & COLITIS, 2024, 18 : I10 - I12
  • [46] Reduction in inflammatory biomarkers in a Phase 2 study of mirikizumab in patients with moderately to severely active ulcerative colitis
    Sandborn, W. J.
    Sands, B.
    Kobayashi, T.
    Tuttle, J.
    Schmitz, J.
    Durante, M.
    Higgs, R.
    Canavan, J. B.
    Siegel, R.
    Ferrante, M.
    JOURNAL OF CROHNS & COLITIS, 2019, 13 : S59 - S60
  • [47] Efficacy and safety of the mirikizumab extended induction cohort at 152 weeks of continuous treatment for moderately to severely active Ulcerative Colitis: Results from the LUCENT-3 open-label extension study
    Hart, A.
    Blumenstein, I
    Kobayashi, T.
    Chaparro, M.
    Fantini, M. C.
    Fumery, M.
    Keohane, A.
    Dhesi, E.
    Tian, T.
    Redondo, I
    Barnes, E. L.
    JOURNAL OF CROHNS & COLITIS, 2025, 19 : i1452 - i1454
  • [48] THE EFFICACY AND SAFETY OF GUSELKUMAB AS MAINTENANCE THERAPY IN PATIENTS WITH MODERATELY TO SEVERELY ACTIVE ULCERATIVE COLITIS: RESULTS FROM THE PHASE 3 QUASAR MAINTENANCE STUDY
    Rubin, David T.
    Allegretti, Jessica R.
    Panes, Julian
    Shipitofsky, Nicole
    Yarandi, Shadi
    Huang, Kuan-Hsiang G.
    Germinaro, Matthew
    Wilson, Rebbecca
    Zhang, Hongyan
    Feagan, Brian G.
    Hisamatsu, Tadakazu
    Lichtenstein, Gary R.
    Bressler, Brian
    Peyrin-Biroulet, Laurent
    Sands, Bruce E.
    Dignass, Axel
    GASTROENTEROLOGY, 2024, 166 (05) : S180 - S180
  • [49] Risankizumab Induction Therapy in Patients With Moderately to Severely Active Ulcerative Colitis: Efficacy and Safety in the Randomized Phase 3 INSPIRE Study
    Louis, Edouard
    Panaccione, Remo
    Parkes, Gareth
    Peyrin-Biroulet, Laurent
    Ferrante, Marc
    Takeuchi, Ken
    Siegmund, Britta
    Levine, Phillip
    Kalabic, Jasmina
    Neimark, Ezequiel
    Wallace, Kori
    Chen, Su
    Duan, W. Rachel
    Armuzzi, Alessandro
    Biedermann, Luc
    Loftus, Edward V.
    Melmed, Gil
    Schreiber, Stefan
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2023, 118 (10): : S624 - S625
  • [50] Risankizumab Induction Therapy in Patients With Moderately to Severely Active Ulcerative Colitis: Efficacy and Safety in the Randomized Phase 3 INSPIRE Study
    Louis, Edouard
    Panaccione, Remo
    Parkes, Gareth
    Pevrin-Biroulet, Laurent
    Ferrante, Marc
    Takeuchi, Ken
    Siegmund, Britta
    Levine, Phillip
    Kalabic, Jasmina
    Neimark, Ezequiel
    Wallace, Kori
    Chen, Su
    Duan, W. Rachel
    Armuzzi, Alessandro
    Biedermann, Luc
    Loftus, Edward
    Melmed, Gil
    Schreiber, Stefan
    AMERICAN JOURNAL OF GASTROENTEROLOGY, 2023, 118 (12S): : S3 - S3