The application of antibiotic-loaded bone cement in preventing periprosthetic joint infection: an umbrella review

被引：0

作者：

Yangbin Cao ^{[1
]}

Peiyuan Tang ^{[3
]}

Hua Chai ^{[1
]}

Wenbo Ma ^{[2
]}

Bin Lin ^{[3
]}

Ying Zhu ^{[3
]}

Ahmed Abdirahman ^{[3
]}

Wenfeng Xiao ^{[3
]}

Jun Zhang ^{[1
]}

Yusheng Li ^{[2
]}

Shuguang Liu ^{[1
]}

Ting Wen ^{[2
]}

机构：

[1] Central South University,Department of Orthopedics, Xiangya Hospital

[2] Central South University,National Clinical Research Center for Geriatric Disorders, Xiangya Hospital

[3] Xiangya School of Medicine,The First People’s Hospital of Changde City, Changde Hospital

[4] Central South University,Department of Joint Surgery

[5] Xiangya Medical College,undefined

[6] Central South University,undefined

[7] Honghui Hospital,undefined

[8] Xi’an Jiaotong University,undefined

来源：

Journal of Orthopaedics and Traumatology | / 26卷 / 1期

关键词：

Prosthesis-related infections; Antibacterial agents; Bone cements; Total joint arthroplasty; Antibiotic prophylaxis;

D O I：

10.1186/s10195-025-00839-w

中图分类号：

学科分类号：

摘要：

This umbrella review included a total of ten meta-analyses.The highest level of evidence to date suggests that antibiotic-loaded bone cement cannot be considered an effective prevention method for periprosthetic joint infection.No statistically significant difference was found on TIR between the two groups, although it was lower in the ALBC group. In addition, the DIR and revision for PJI are significantly lower in the ALBC group, but the results are of low quality, which calls for high-quality and large-sample studies in the future.

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