Quantitation of adeno-associated virus in a dual-vector system using sedimentation velocity analytical ultracentrifugation

被引：0
|
作者：
Yarawsky, Alexander E. [1 ]
Ciatto, Carlo [2 ]
Slade, Peter [2 ]
Figueroa, Natalya I. [1 ]
Burgner, John W.
Delion, Michael T. [1 ]
Paul, Lake N. [1 ]
机构：
[1] BioAnalysis LLC, 3401 1 St Suite 206, Philadelphia, PA 19134 USA
[2] Decibel Therapeut Inc, 1325 Boylston St Suite 500, Boston, MA 02215 USA
来源：
JOURNAL OF PHARMACEUTICAL SCIENCES | 2025年 / 114卷 / 02期
关键词：
Adeno-associated virus; Analytical ultracentrifugation; Viral vector; Polymerase chain reaction; Biopharmaceutical characterization; Triple-vector; Gene therapy; Physicochemical properties; SIZE-DISTRIBUTION ANALYSIS; DISTRIBUTIONS;
D O I：
10.1016/j.xphs.2024.10.049
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
lpaul@bioanalysisllc.com
引用
收藏
页码：900 / 910
页数：11
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