Exploring the Mechanisms and Dosages of Herbal Hepatoprotective Agents

被引:0
|
作者
Rajappa, Rajendra Prasad Menasagere [1 ,2 ]
Nallupillai, Paramakrishnan [1 ]
Krishna, Kamsagara Linganna [3 ]
Ramesh, Manoj Madanahalli [4 ]
Venkatappa, Annegowda Hardur [4 ]
机构
[1] JSS Acad Higher Educ & Res, JSS Coll Pharm, Dept Pharmacognosy, Mysuru 570015, Karnataka, India
[2] Farooqia Coll Pharm, Dept Pharmacognosy, Mysore, Karnataka, India
[3] JSS Acad Higher Educ & Res, JSS Coll Pharm, Dept Pharmacol, Mysuru, Karnataka, India
[4] Adichunchanagiri Univ, Sri Adichunchanagiri Coll Pharm, Fac Pharm, Dept Pharmacognosy, Mandya, Karnataka, India
来源
PHARMACOGNOSY RESEARCH | 2024年 / 16卷 / 04期
关键词
Herbal Drugs; Hepatoprotective Agents; Mechanism; Dosage; Patents; Market Size; ORTHOSIPHON-STAMINEUS; SILYBUM-MARIANUM; ANDROGRAPHIS-PANICULATA; OXIDATIVE STRESS; LIVER; DISEASE; ANTIOXIDANT; EXTRACT; L; PHARMACOLOGY;
D O I
10.5530/pres.16.4.82
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Herbal hepatoprotective drugs are important for managing liver health because they provide complementary or alternative treatments for the various disorders of the liver. This review provides a thorough analysis of the numerous herbal hepatoprotective drugs' studied during the recent years, including their modes of action, suggested dosages, market trends, status of clinical trials and patents. The hepatoprotective properties of these herbal medicinal products are partly attributed to their mechanisms of actions such as antioxidant, anti-inflammatory, enzyme-modulating actions, and regeneration of hepatocytes. The recommended dosages differ based on the particular plant and ailment, highlighting the necessity for individualized treatment plans and more research to achieve the best possible therapeutic results. Patented compositions and polyherbal formulations provide novel treatments with synergistic effects that improve medicinal efficacy. The increased demand for natural treatments and their potential applications in pharmaceutical and nutraceutical fields has resulted in a considerable and expanding market for herbal hepatoprotective agents. Notwithstanding their possible advantages, more investigation is required to clarify mechanisms of action, assess long-term safety and efficacy, and provide uniform standards for clinical application. In general, herbal hepatoprotective drugs are promising approaches to manage liver health; nonetheless, their use necessitates regulatory oversight, quality control procedures, and evidence-based practice.
引用
收藏
页码:706 / 717
页数:12
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