Single-cell transcriptomics of CD8 T cells in autoimmune diabetes after anti-CD3 monoclonal antibody treatment

被引：0
|
作者：
Wu, Ying [1 ]
Spurrell, Maxwell [1 ]
Deng, Songyan [1 ]
Herold, Kevan [1 ]
机构：
[1] Yale Sch Med, New Haven, CT USA
来源：
JOURNAL OF IMMUNOLOGY | 2024年 / 212卷 / 01期
关键词：
D O I：
10.4049/jimmunol.212.supp.0998.4625
中图分类号：
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
引用
收藏
页数：2
相关论文
共 50 条
  • [31] Acquisition of regulatory function by human CD8+ T cells treated with anti-CD3 antibody requires TNF
    Ablamunits, Vitaly
    Bisikirska, Brygida
    Herold, Kevan C.
    EUROPEAN JOURNAL OF IMMUNOLOGY, 2010, 40 (10) : 2891 - 2901
  • [32] Single-Cell Transcriptomics Identifies TOX as a Key Transcriptional Regulator of Stem- Like CD8 T Cells in Chronic Infection
    Wu, Tuoqi
    Yao, Chen
    Sun, Hongwei
    Lacey, Neal
    Gattinoni, Luca
    McGavern, Dorian B.
    O'Shea, John J.
    Schwartzberg, Pamela L.
    JOURNAL OF IMMUNOLOGY, 2019, 202 (01):
  • [33] Anti-CD3 monoclonal antibody in new-onset type 1 diabetes mellitus
    Herold, KC
    Hagopian, W
    Auger, JA
    Poumian-Ruiz, E
    Taylor, L
    Donaldson, D
    Gitelman, SE
    Harlan, DM
    Xu, DL
    Zivin, RA
    Bluestone, JA
    NEW ENGLAND JOURNAL OF MEDICINE, 2002, 346 (22): : 1692 - 1698
  • [34] In vitro induction of regulatory T cells by anti-CD3 antibody in humans
    Abraham, Michal
    Karni, Arnon
    Dembinsky, Adi
    Miller, Ariel
    Gandhi, Roopali
    Anderson, David
    Weiner, Howard L.
    JOURNAL OF AUTOIMMUNITY, 2008, 30 (1-2) : 21 - 28
  • [35] Phased differentiation of γδ T and T CD8 tumor-infiltrating lymphocytes revealed by single-cell transcriptomics of human cancers
    Cerapio, Juan-Pablo
    Perrier, Marion
    Balanca, Camille-Charlotte
    Gravelle, Pauline
    Pont, Frederic
    Devaud, Christel
    Franchini, Don-Marc
    Feliu, Virginie
    Tosolini, Marie
    Valle, Carine
    Lopez, Frederic
    Quillet-Mary, Anne
    Ysebaert, Loic
    Martinez, Alejandra
    Delord, Jean Pierre
    Ayyoub, Maha
    Laurent, Camille
    Fournie, Jean-Jacques
    ONCOIMMUNOLOGY, 2021, 10 (01):
  • [36] Leveraging single-cell sequencing to discover novel exhaustion markers of CD8 T cells
    Shi, Xiaoshan
    Jayaram, Savita
    Lee, Kayla
    Bhojak, Keshav
    Kode, Vasumathi
    Chaudhary, Mridul
    Patil, Ashwini
    Gupta, Ravi
    Chaudhuri, Amit
    Chakraborty, Papia
    CANCER RESEARCH, 2019, 79 (13)
  • [37] Proteolytic cleavage of alpha-actinin by calpain in T cells stimulated with anti-CD3 monoclonal antibody
    Selliah, N
    Brooks, WH
    Roszman, TL
    JOURNAL OF IMMUNOLOGY, 1996, 156 (09): : 3215 - 3221
  • [38] Use of anti-CD3 monoclonal antibody to induce immune regulation in type 1 diabetes
    Bisikirska, BC
    Herold, KC
    IMMUNOLOGY OF DIABETES III, 2004, 1037 : 1 - 9
  • [39] Reversal of Experimental Autoimmune Diabetes With an sCD39/Anti-CD3 Treatment
    Fotino, Carmen
    Molano, R. Damaris
    Ben Nasr, Moufida
    Umland, Oliver
    Fraker, Christopher A.
    Ulissi, Ulisse
    Balasubramanian, Hari Baskar
    Lunati, Maria Elena
    Usuelli, Vera
    Seelam, Andy Joe
    Khalefa, Salma Ayman
    La Sala, Christian
    Gimeno, Jennifer
    Mendez, Armando J.
    Ricordi, Camillo
    Bayer, Allison L.
    Fiorina, Paolo
    Pileggi, Antonello
    DIABETES, 2023, 72 (11) : 1641 - 1651
  • [40] ANTI-CD3 ANTIBODY FOR AUTOIMMUNE-DISEASE, A CAUTIONARY NOTE
    HIRSCH, R
    GRESS, RE
    BLUESTONE, JA
    LANCET, 1989, 1 (8651): : 1390 - 1390
12345