Generation of Off-the-Shelf CAR Gamma Delta T Cells Using CRISPR and AAV, a New Era in Cell Therapy

被引：0
|
作者：
Snyder, Genesis [1 ]
Martin, Alexia [1 ]
Esfahani, Noushin Saljoughian [1 ]
Maguire, Colin [1 ]
Lee, Dean A. [2 ]
Kararoudi, Meisam Naeimi [1 ,3 ]
机构：
[1] Nationwide Childrens Hosp, Columbus, OH USA
[2] Nationwide Childrens Hosp, Canal Winchester, OH USA
[3] Ohio State Univ, Columbus, OH USA
来源：
MOLECULAR THERAPY | 2024年 / 32卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q81 [生物工程学（生物技术）]; Q93 [微生物学];
学科分类号：
071005 ; 0836 ; 090102 ; 100705 ;
摘要：
411
引用
收藏
页码：224 / 224
页数：1
相关论文
共 50 条
  • [21] Improvement of "off-the-shelf'' allogeneic CAR-T cells
    Pavlovic, K.
    Carmona, M. D.
    Maldonado, N.
    Tristan, M.
    Cortijo, M.
    Nogueras, S.
    Jimenez, R.
    Martin, F.
    Herrera, I. C.
    Benabdellah, K.
    HUMAN GENE THERAPY, 2021, 32 (19-20) : A87 - A87
  • [22] Engineered hypoimmune allogeneic CAR T cells as potential off-the-shelf CAR T cell immunotherapies.
    Hu, Xiaomeng
    White, Kathy
    Gattis, Corie
    Clarke, Ryan
    Landry, Sam
    Basco, Ron
    Tham, Eleonore
    Luo, Emily
    Tucker, Andrew
    Bandoro, Christopher
    Chu, Elaine
    Young, Chi
    Manner, Karl
    Nho, Priscilla
    Lam, Ben
    Beauchesne, Pascal
    Foster, Aaron
    Dowdle, William E.
    Rebar, Edward J.
    Fry, Terry J.
    Schrepfer, Sonja
    CANCER RESEARCH, 2022, 82 (12)
  • [23] Development of Next Generation CAR T Cell Therapy for the Off-the-shelf Treatment of Autoimmune Diseases Without Conditioning Chemotherapy
    Goulding, John
    Reiser, John
    O'Connor, Alison
    Hancock, Bryan
    Tuncel, Jonatan
    Groff, Brian
    Mbofung, Rina
    Morales-Mantilla, Daniel
    Williams, Allan
    Lu, Dan
    Yang, Bi-Huei
    Peralta, Eigen
    Gutierrez, Alma
    Meza, Miguel
    Rezner, Betsy
    Sims, Amanda
    Witty, Alec
    Pan, Yijia
    Jelcic, Mark
    Sikaroodi, Shohreh
    Denholtz, Matthew
    Lee, Tom
    Bagri, Anil
    Wong, Lilly
    Goodridge, Jode
    Valamehr, Bahram
    ARTHRITIS & RHEUMATOLOGY, 2024, 76 : 3760 - 3761
  • [24] "Off-the-Shelf" CAR T-Cell Therapy Tested in Pediatric B-Cell Leukemia
    Larkin, Howard
    JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 2022, 328 (22): : 2201 - 2201
  • [25] The paths and challenges of "off-the-shelf" CAR-T cell therapy: An overview of clinical trials
    Moradi, Vahid
    Omidkhoda, Azadeh
    Ahmadbeigi, Naser
    BIOMEDICINE & PHARMACOTHERAPY, 2023, 169
  • [26] Potent, CRISPR-engineered off-the-shelf CAR-T and TCR-T cells evading host T and NK cell rejection
    Zhang, Y.
    Prodeus, A.
    Yetley, U.
    Tan, Y.
    Ranade, U.
    Balwani, I.
    Liu, D.
    Miller, I.
    Zhang, B.
    Dutta, I.
    Sharma, P.
    Goel, S.
    Malik, V.
    Venkatesan, P.
    Keenan, M.
    Lam, M.
    Arredouani, S.
    Schultes, B. C.
    HUMAN GENE THERAPY, 2022, 33 (23-24) : A128 - A128
  • [27] “Off-the-Shelf” Allogeneic CAR Cell Therapy—Neglected HvG Effect
    Yuxin An
    Xin Jin
    Hongkai Zhang
    Meng Zhang
    Sadhana Mahara
    Wenyi Lu
    Mingfeng Zhao
    Current Treatment Options in Oncology, 2023, 24 : 409 - 441
  • [28] Rejection-Resistant Off-the-Shelf T Cells for Adoptive Cell Therapy
    Mo, Feiyan
    Srinivasan, Madhuwanti
    Heslop, Helen E.
    Brenner, Malcolm K.
    Mamonkin, Maksim
    BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION, 2019, 25 (03)
  • [29] Rejection-Resistant Off-The-Shelf T Cells for Adoptive Cell Therapy
    Mo, Feiyan
    Srinivasan, Madhuwanti
    Ma, Royce
    Smith, Tyler S.
    McKenna, Mary K.
    Atilla, Erden
    Atilla, Pinar Ataca
    Heslop, Helen E.
    Brenner, Malcolm K.
    Mamonkin, Maksim
    MOLECULAR THERAPY, 2019, 27 (04) : 64 - 64
  • [30] Use of Cell and Genome Modification Technologies to Generate Improved "Off-the-Shelf" CAR T and CAR NK Cells
    Morgan, Michael A.
    Buening, Hildegard
    Sauer, Martin
    Schambach, Axel
    FRONTIERS IN IMMUNOLOGY, 2020, 11
12345