A case of frequent of prerenal acute kidney injury attacks: importance of recognizing systemic capillary leak syndrome: a case report

被引:0
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作者
Miyazawa, Reina [1 ]
Nakamura, Hironori [1 ]
Kumagai, Michiko [1 ]
Anayama, Mariko [1 ]
Makino, Yasushi [1 ]
Nishikawa, Marina [2 ]
Hashimoto, Koji [2 ]
Kamijo, Yuji [2 ]
机构
[1] SHINONOI GEN HOSP, Dept Nephrol, 666-1 Ai Shinonoi, Nagano 3888004, Japan
[2] Shinshu Univ Hosp, Dept Nephrol, Matsumoto, Japan
关键词
Case report; hypotension; haemoconcentration; hypoalbuminaemia;
D O I
10.1177/03000605241301863
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Systemic capillary leak syndrome (SCLS) is a rare and life-threatening disorder. A man in his 60s presented for emergency care because of fatigue, decreased urine output and difficulty in moving his body. On admission, he was conscious, afebrile and had relative hypotension. Blood tests and urinary analysis revealed the following: white blood cell count, 19 500/mu l; haematocrit, 64.5%; creatinine, 2.16 mg/dl; albumin, 3.3 g/dl; and 0.2% for fractional excretion of sodium. The patient was diagnosed with prerenal acute kidney injury (AKI) and was treated with intravenous fluid administration of more than 2 l/day. His kidney function gradually recovered after 4 days and creatinine decreased (1.15 mg/dl). However, he developed two more attacks of prerenal AKI during hospitalization, one of which needed intensive care unit management. Specific findings of hypotension, haemoconcentration, and hypoalbuminaemia were observed during all AKI attacks. Finally, he was diagnosed as idiopathic SCLS and was treated with intravenous immunoglobulin. SCLS might remain undiagnosed because of its rarity, but it can rapidly progress and lead to severe complications in absence of treatment. Clinicians need to consider this disease as a differential diagnosis when encountering patients who present with frequent prerenal AKI attacks accompanied by hypotension, haemoconcentration and hypoalbuminaemia.
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页数:7
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