Management and predictors of event-free survival in nonagenarians with myocardial infarction: A nationwide analysis

被引：0

作者：

Kupisz-Urbanska, Malgorzata ^{[1
,2
]}

Jankowski, Piotr ^{[2
,3
]}

Ceglowska, Urszula ^{[3
]}

Teisseyre, Pawel ^{[4
,5
,6
]}

Buszman, Piotr ^{[7
]}

Danilowicz-Szymanowicz, Ludmila ^{[8
]}

Dorynska, Agnieszka

Drozdz, Jaroslaw ^{[9
]}

Gasior, Mariusz ^{[10
]}

Gil, Robert ^{[11
,12
]}

Gromadzinski, Leszek ^{[13
]}

Jaguszewski, Milosz ^{[14
]}

Jaroch, Joanna ^{[15
]}

Kasprzak, Jaroslaw ^{[16
]}

Komar, Monika ^{[17
]}

Kubica, Jacek ^{[18
]}

Leszek, Przemyslaw ^{[19
]}

Pinkas, Jaroslaw ^{[20
]}

Rajzer, Marek ^{[21
]}

Stepinska, Janina ^{[22
]}

Surdacki, Andrzej ^{[23
]}

Tomkiewicz-Pajak, Lidia ^{[15
]}

Topor-Madry, Roman ^{[4
,24
]}

Wacinski, Piotr ^{[25
]}

Witkowski, Adam ^{[26
]}

Wysokinski, Andrzej ^{[27
]}

Niewada, Maciej ^{[28
]}

Gellert, Ryszard ^{[29
]}

机构：

[1] Ctr Postgrad Med Educ, Dept Geriatr, DEPT PHARMACOL, PL-00927 Warsaw, Poland

[2] Ctr Postgrad Med Educ, Dept Internal Med & Geriatr Cardiol, Czerniakowska 231, PL-00416 Warsaw, Poland

[3] Ctr Postgrad Med Educ, Sch Publ Hlth, Dept Epidemiol & Hlth Promot, Warsaw, Poland

[4] Agcy Hlth Technol Assessment & Tariff Syst, Warsaw, Poland

[5] Polish Acad Sci, Inst Comp Sci, PL-00818 Warsaw, Poland

[6] Warsaw Univ Technol, Fac Math & Informat Sci, Warsaw, Poland

[7] Ctr Cardiol & Cardiac Surg Amer Heart Poland, Bielsko Biala, Poland

[8] Med Univ Gdansk, Fac Med, Dept Cardiol & Electrotherapy, Gdansk, Poland

[9] Med Univ Lodz, Dept Cardiol 2, Lodz, Poland

[10] Med Univ Silesia, Fac Med Sci Zabrze, Dept Cardiol 3, Katowice, Poland

[11] Ctr Postgrad Med Educ, Dept Invas Cardiol, Warsaw, Poland

[12] Minist Interior & Adm, Natl Med Inst, Warsaw, Poland

[13] Univ Warmia & Mazury, Sch Med, Dept Cardiol & Internal Med, Coll Med, Olsztyn, Poland

[14] Med Univ Gdansk, Dept Cardiol 1, Gdansk, Poland

[15] T Marciniak Lower Silesian Specialist Hosp, Emergency Med Ctr, Dept Cardiol, Wroclaw, Poland

[16] Med Univ Lodz, Bieganski Hosp, Dept Cardiol 1, Lodz, Poland

[17] Jagiellonian Univ, Med Coll, Inst Cardiol, Krakow, Poland

[18] Nicolaus Copernicus Univ, Dept Cardiol & Internal Med, Intervent Cardiol & Cardiovasc Med Res, Bydgoszcz, Poland

[19] Cardinal Stefan Wyszynski Inst Cardiol Warsaw, Dept Heart Failure & Transplantat Med, Warsaw, Poland

[20] Ctr Postgrad Med Educ, Sch Publ Hlth, Warsaw, Poland

[21] Jagiellonian Univ Med Coll, Inst Cardiol, Dept Cardiol Intervent Electrocardiol & Hypertens, Krakow, Poland

[22] Natl Inst Geriatr Rheumatol & Rehabil, Warsaw, Poland

[23] Jagiellonian Univ Med Coll, Inst Cardiol, Dept Cardiol 2, Krakow, Poland

[24] Jagiellonian Univ, Med Coll, Krakow, Poland

[25] SPSK4 Univ Hosp, Dept Intervent Cardiol, Lublin, Poland

[26] Natl Inst Cardiol, Dept Intervent Cardiol & Angiol, Warsaw, Poland

[27] Med Univ Lublin, Dept Cardiol, Lublin, Poland

[28] Med Univ Warsaw, Dept Expt & Clin Pharmacol, Warsaw, Poland

[29] Ctr Postgrad Med Educ, Dept Nephrol Internal Med & Family Med, Warsaw, Poland

来源：

POLISH HEART JOURNAL-KARDIOLOGIA POLSKA | 2025年 / 83卷 / 02期

关键词：

cardiovascular events; coronary artery disease; mortality; myocardial infarction; oldest olds; nonagenarians; OUTCOMES; AGE;

D O I：

10.33963/v.phj.103771

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Background: Myocardial infarction (MI) remains the leading cause of death, especially in the elderly. Aims:To characterize management and factors related to event-free survival in patients with acute MI aged at least 90 years. Methods: We included all patients aged at least 90 years hospitalized for MI in Poland between 2014 and 2020 and followed them for one year. Results: A total of 14 970 patients (median age 92.7 [90.9-93.8] years) were included (4666 men and 10 304 women). Coronary angiography was performed in 47.0% of patients, percutaneous coronary intervention in 39.8%, and coronary artery bypass grafting in 0.2%. In-hospital mortality was 27.8% (25.1% in men and 29.0% in women; P <0.001). Variables independently related to the higher risk of in-hospital death were age and history of stroke, while male sex, hypertension, history of MI, and invasive management were related to a lower risk of in-hospital death. One-year all-cause mortality following discharge was 38.1% (females: 38.4%, males: 37.5%; P = 0.27), the endpoint consisting of all-cause death, MI, or stroke occurred in 42.6% patients (females: 42.8%, males: 42.2%; P = 0.44), while all-cause death or cardiovascular hospitalization occurred in 59.0% (females: 58.2%, males: 60.7%; P = 0.046). Variables independently related to the higher risk of post-discharge death were age, heart failure, atrial fibrillation, diabetes, and chronic obstructive pulmonary disease. Participation in the managed care program following MI was linked to a lower risk of death or hospitalization for cardiovascular reasons. Conclusions: Variables independently related to the higher risk of post-discharge death among patients hospitalized for MI aged at least 90 years were age, heart failure, atrial fibrillation, diabetes, and chronic obstructive pulmonary disease.When managed invasively, males have lower in-hospital mortality but higher post-discharge mortality than females.

引用

页码：149 / 156

页数：8

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