Challenges in tacrolimus dosing in mutant CYP3A5*3/3*renal transplant patients leading to over immunosuppression and persistent post-transplant covid viremia

被引:0
|
作者
Chauhan, Sanjeev [1 ]
Sharma, Ashish [1 ]
Kenwar, Deepesh Benjamin [1 ]
Singh, Sarbpreet [1 ]
Patil, Shiva Kumar [1 ]
Patniak, Samita [2 ]
Karthik, Nasika Venkata Kanaka Naga [1 ]
Panjathia, Arun [1 ]
Bhushan, Bharat [1 ]
Reddy, Perugu Sai Praneeth [1 ]
Gysley, Belmin Winston [1 ]
机构
[1] Post Grad Inst Med Educ & Res, Ranal Transplant Surg, Chandigarh, India
[2] Post Grad Inst Med Educ & Res, Clin Pharmacol, Chandigarh, India
关键词
D O I
暂无
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
P.075
引用
收藏
页码:482 / 482
页数:1
相关论文
共 50 条
  • [31] Tacrolimus dosing in pediatric heart transplant patients is related to CYP3A5 and MDR1 gene polymorphisms
    Zheng, HX
    Webber, S
    Zeevi, A
    Schuetz, E
    Zhang, J
    Bowman, P
    Boyle, G
    Law, Y
    Miller, S
    Lamba, J
    Burckart, GJ
    AMERICAN JOURNAL OF TRANSPLANTATION, 2003, 3 (04) : 477 - 483
  • [32] Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population
    Lalan, Shwetal
    Abdel-Rahman, Susan
    Gaedigk, Andrea
    Leeder, J. Steven
    Warady, Bradley A.
    Dai, Hongying
    Blowey, Douglas
    PEDIATRIC NEPHROLOGY, 2014, 29 (10) : 2039 - 2049
  • [33] CYP3A5 Genotype and Time to Reach Tacrolimus Therapeutic Levels in Renal Transplant Children
    Alvarez-Eliasa, A. C.
    Garcia-Rocaa, P.
    Velasquez-Jones, L.
    Valverde, S.
    Varela-Fascinetto, G.
    Medeiros, M.
    TRANSPLANTATION PROCEEDINGS, 2016, 48 (02) : 631 - 634
  • [34] EFFECT OF CYP3A5, CYP3A4, POR AND ABCB1 POLYMORPHISMS ON TACROLIMUS METABOLISM IN RENAL TRANSPLANT PATIENTS
    Chong, Winnie
    Hamilton-Jones, Siobhan
    Kim, Jon Jin
    Navarrete, Cristina V.
    Key, Tim
    Howell, Martin W.
    HLA, 2020, 95 (04) : 316 - 316
  • [35] Effect of CYP3A5 genotype, steroids, and azoles on tacrolimus in a pediatric renal transplant population
    Shwetal Lalan
    Susan Abdel-Rahman
    Andrea Gaedigk
    J. Steven Leeder
    Bradley A. Warady
    Hongying Dai
    Douglas Blowey
    Pediatric Nephrology, 2014, 29 : 2039 - 2049
  • [36] The population pharmacokinetics of sirolimus and CYP3A5*3 polymorphism in Chinese renal transplant patients
    Shi, Hao-Qiang
    Yang, Jun
    Zhang, Li-Qun
    Xu, Bei-Ming
    Lu, Hui-Lan
    Chen, Er-Zhen
    Chen, Bing
    INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE, 2016, 9 (03): : 5854 - 5866
  • [37] Effect of drug combination on tacrolimus target dose in renal transplant patients with different CYP3A5 genotypes
    Zhang, Shu-Fang
    Tang, Bo-Hao
    Wei, An-Hua
    Du, Yue
    Guan, Zi-Wan
    Li, Yan
    XENOBIOTICA, 2022, 52 (03) : 312 - 321
  • [38] Frequencies of CYP3A5*1/*3 Variants in a Moroccan Population and Effect on Tacrolimus Daily Dose Requirements in Renal Transplant Patients
    Elmachad, Mustapha
    Elkabbaj, Driss
    Elkerch, Fatiha
    Laarabi, Fatima Zahra
    Barkat, Amina
    Oualim, Zouhir
    Sefiani, Abdelaziz
    GENETIC TESTING AND MOLECULAR BIOMARKERS, 2012, 16 (06) : 644 - 647
  • [39] ASSOCIATION BETWEEN TACROLIMUS AND CYP3A5 GENOTYPE IN PEDIATRIC KIDNEY TRANSPLANT
    Alghamdi, A.
    Lazear, D.
    Varnell, C.
    Seay, S.
    Hooper, D.
    Darland, L.
    Mizuno, T.
    Ramsey, L.
    CLINICAL PHARMACOLOGY & THERAPEUTICS, 2023, 113 : S10 - S10
  • [40] Age and CYP3A5 genotype affect tacrolimus dosing requirements after transplant in pediatric heart recipients
    Gijsen, Violette
    Mital, Seema
    van Schaik, Ron H.
    Soldin, Offie P.
    Soldin, Steven J.
    van der Heiden, Ilse P.
    Nulman, Irena
    Koren, Gideon
    de Wildt, Saskia N.
    JOURNAL OF HEART AND LUNG TRANSPLANTATION, 2011, 30 (12): : 1352 - 1359