Radical-mediated chemo-divergent recyclization of 1,2,3,4-benzothiatriazine-1,1-dioxides: alkyl migration and dearomatization

被引：0

作者：

Nan, Jiang ^{[1
]}

Yang, Shuai ^{[1
]}

Huang, Guanjie ^{[1
]}

Fan, Liangxin ^{[2
]}

机构：

[1] Shaanxi Univ Sci & Technol, Coll Chem & Chem Engn, Key Lab Chem Addit China Natl Light Ind, Xian 710021, Peoples R China

[2] Henan Agr Univ, Coll Sci, Zhengzhou 450002, Peoples R China

来源：

CHEMICAL COMMUNICATIONS | 2025年 / 61卷 / 29期

关键词：

ASYMMETRIC DEAROMATIZATION; ISOMERIZATION; CYCLIZATION;

D O I：

10.1039/d5cc00008d

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A divergent denitrogenation/recyclization of 1,2,3,4-benzothiatriazine-1,1-dioxides is disclosed, including C(sp2)-alkyl transposition and aniline dearomatization. Regarding the alkyl migration process, a rare radical-mediated model is presented. Synthetically, sterically-congested biaryl sultams and ortho-all carbon quaternary stereocenter-substituted imines are expeditiously assembled in a simple reaction system. Mechanistic insights indicate that an innovative pattern of diradical-triggered addition probably plays an essential role in the process of C(sp2)-alkyl transformation.

引用

页码：5503 / 5506

页数：4