Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia

被引：0
|
作者：
Lin, Shan [1 ,2 ,3 ]
Kotliar, Michael [4 ]
Vallabh, Sushmitha [4 ]
Ptasinska, Anetta [2 ,5 ]
Assi, Salam A. [2 ,5 ]
Wunderlich, Mark [1 ]
Bonifer, Constanze [2 ,5 ]
Barski, Artem [4 ,6 ,7 ]
Mulloy, James C. [1 ,7 ]
机构：
[1] Cincinnati Childrens Hosp Med Ctr, Div Expt Hematol & Canc Biol, Cincinnati, OH USA
[2] Seattle Childrens Res Inst, Ben Towne Ctr Childhood Canc & Blood Disorders Res, Seattle, WA USA
[3] Univ Washington, Dept Pediat, Seattle, WA USA
[4] Cincinnati Childrens Hosp Med Ctr, Div Allergy & Immunol, Cincinnati, OH USA
[5] Univ Birmingham, Inst Canc & Genom Sci, Coll Med & Dent, Birmingham, England
[6] Cincinnati Childrens Hosp Med Ctr, Div Human Genet, Cincinnati, OH USA
[7] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA
来源：
BLOOD ADVANCES | 2025年 / 9卷 / 04期
基金：
美国国家卫生研究院;
关键词：
GENE-EXPRESSION; DISTINCT; MLL-AF4; INHIBITION; RESISTANCE; LANDSCAPE;
D O I：
10.1182/bloodadvances.2024014065
中图分类号：
R5 [内科学];
学科分类号：
1002 ; 100201 ;
摘要：
引用
收藏
页码：856 / 861
页数：6
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