Fusion-specific chromatin profiles mediate transcriptional heterogeneity in MLL-rearranged acute lymphoblastic leukemia

被引：0

作者：

Lin, Shan ^{[1
,2
,3
]}

Kotliar, Michael ^{[4
]}

Vallabh, Sushmitha ^{[4
]}

Ptasinska, Anetta ^{[2
,5
]}

Assi, Salam A. ^{[2
,5
]}

Wunderlich, Mark ^{[1
]}

Bonifer, Constanze ^{[2
,5
]}

Barski, Artem ^{[4
,6
,7
]}

Mulloy, James C. ^{[1
,7
]}

机构：

[1] Cincinnati Childrens Hosp Med Ctr, Div Expt Hematol & Canc Biol, Cincinnati, OH USA

[2] Seattle Childrens Res Inst, Ben Towne Ctr Childhood Canc & Blood Disorders Res, Seattle, WA USA

[3] Univ Washington, Dept Pediat, Seattle, WA USA

[4] Cincinnati Childrens Hosp Med Ctr, Div Allergy & Immunol, Cincinnati, OH USA

[5] Univ Birmingham, Inst Canc & Genom Sci, Coll Med & Dent, Birmingham, England

[6] Cincinnati Childrens Hosp Med Ctr, Div Human Genet, Cincinnati, OH USA

[7] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA

来源：

BLOOD ADVANCES | 2025年 / 9卷 / 04期

基金：

美国国家卫生研究院;

关键词：

GENE-EXPRESSION; DISTINCT; MLL-AF4; INHIBITION; RESISTANCE; LANDSCAPE;

D O I：

10.1182/bloodadvances.2024014065

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：856 / 861

页数：6

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